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OP80 Anti-APC (Ab-7) Mouse mAb (CC-1)

OP80
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Species ReactivityHostAntibody Type
H, M, RMMonoclonal Antibody

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OP80-100UG
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      Ampoule plast. 100 μg
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      Description
      OverviewRecognizes APC in oligodendrocytes and astrocytes.
    • Antibody Target Gene Symbol: APC
    • Target Synonym: AI047805, Apc7, AU020952, AW124434, BTPS2, DP2, DP2.5, DP3, Familial adenomatous polyposis, FAP, GS, Min, RATAPC
    • Entrez Gene Name: adenomatous polyposis coli
    • Hu Entrez ID: 324 (Related Antibodies: ST1150, OP62, OP47L, OP44)
    • Mu Entrez ID: 11789
    • Rat Entrez ID: 24205
    • Catalogue NumberOP80
      Brand Family Calbiochem®
      SynonymsAnti-Adenomatus Polyposis Coli
      References
      ReferencesBhat, R.V., et al. 1996. Glia 17, 169.
      Bhat, R.V., et al. 1994. Neuroscience Proceedings.
      Smith, K.J., et al. 1994. Cancer Res. 54, 3672.
      Smith, K.J., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 2846.
      Su, L.-K., et al. 1993. Cancer Res. 53, 2728.
      Su, L.-K., et al. 1993. Science 262, 1734.
      Groden, J., et al. 1991. Cell 66, 589.
      Kinzler, K.W., et al. 1991. Science 251, 1366.
      Product Information
      FormLiquid
      FormulationIn 50 mM sodium phosphate buffer, 0.2% gelatin.
      Negative controlMOPC 21 cells
      Positive controlPurkinje cells or cerebellum tissue
      Preservative≤0.1% sodium azide
      Quality LevelMQ100
      Applications
      Application ReferencesImmunocytochemistry McTigue, D.M., et al. 2001. J. Neurosci. 21, 3392. Free Floating Sections Ding, H., et al. 2003. Cancer Res. 63, 1106.
      Key Applications Free-floating Sections
      Frozen Sections
      Immunocytochemistry
      Immunofluorescence
      Paraffin Sections
      Application NotesFrozen Sections (5 µg/ml)
      Immunofluorescence (5 µg/ml)
      Paraffin Sections (5 µg/ml, heat pre-treament required)
      Immunocytochemistry (see application references)
      Free Floating Sections (see application references)
      Application CommentsWell suited for IHC and IF studies of oligodendrocytes and optic nerves due to the antibody's staining of the cell body as opposed to the myelinated processes. Both frozen sections and formalin-fixed, paraffin-embedded brain sections can be used. Antibody should be titrated for optimal results in individual systems.
      Biological Information
      Immunogena recombinant protein consisting of amino acids 1-226 of APC
      CloneCC-1
      HostMouse
      IsotypeIgG2b
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypeMonoclonal Antibody
      Concentration Label Please refer to vial label for lot-specific concentration
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Yes
      Global Trade Item Number
      Référence GTIN
      OP80-100UG 04055977209662