Millipore Sigma Vibrant Logo

176905 Anthrax Protective Antigen, Bacillus anthracis, Recombinant, B. anthracis - Calbiochem

Anthrax Protective Antigen, Bacillus anthracis, Recombinant, is the protective antigen that mediates the entry of anthrax lethal factor and edema factor into the target cell.

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
View Products on Sigmaaldrich.com
176905
Voir les Prix & la Disponibilité

Aperçu

Prix & Disponibilité

Référence DisponibilitéConditionnement Qté Prix Quantité
176905-100UG
—
Disponibilité limitée Disponibilité limitée
En stock 
Interrompu(e)
Disponible en quantités limitées
Disponibilité à confirmer
    Pour le restant : Nous vous tiendrons informé
      Pour le restant : Nous vous tiendrons informé
      Nous vous tiendrons informé
      Contacter le Service Clients
      Contact Customer Service

      		 Ampoule plast. 100 μg
      Le prix n'a pas pu être récupéré
      La quantité minimale doit être un multiple de
      Maximum Quantity is
      À la validation de la commande Plus d'informations
      Vous avez sauvegardé ()
       
      —
      Demander le prix
      		 —
      Ajouter aux favoris
      Description
      OverviewRecombinant, Bacillus anthracis anthrax protective antigen expressed in a specialized strain of B. anthracis. One of the three protein components of Anthrax toxin, protective antigen (PA) is the central moiety that mediates the entry of lethal factor and edema factor into the target cell. PA binds to the cell surface via a type I membrane protein with a von Willebrand factor A domain called anthrax toxin receptor. After proteolytic activation to a 63 kDa fragment, PA self-associates to form a heptameric cation-selective, voltage-gated membrane channel.
      Catalogue Number176905
      Brand Family Calbiochem®
      References
      ReferencesMogridge, J., et al. 2002. Biochemistry 41, 1079.
      Nassi, S., et al. 2002. Biochemistry 41, 1445.
      Ahuja, N., et al. 2001. Biochem. Biophys. Res. Commun. 286, 6.
      Bradley, K.A., et al. 2001. Nature 414, 225.
      Brossier, F., and Mock, M. 2001. Toxicon 39, 1747.
      Product Information
      ATP CompetitiveN
      FormLyophilized
      FormulationLyophilized from 50 mM NaCl, 5 mM HEPES, pH 7.5.
      ReversibleN
      Quality LevelMQ100
      Applications
      ApplicationAnthrax Protective Antigen, Bacillus anthracis, Recombinant, is the protective antigen that mediates the entry of anthrax lethal factor and edema factor into the target cell.
      Biological Information
      Primary TargetType I membrane protein with a von Willebrand factor A domain called anthrax toxin receptor
      PuritySingle major band by SDS-PAGE. Several smaller minor components are apparent that may represent cleavage fragments of the PA.
      Physicochemical Information
      Cell permeableN
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 6 months at -20°C.
      End use certificateY
      Global Trade Item Number
      Référence GTIN
      176905-100UG 04055977223040