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505145 (+)-Tubocurarine Chloride - CAS 57-94-3 - Calbiochem

FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: Nicotinic Acetylcholine Receptor Antagonist, (+)-Tubocurarine chloride, D-tubocurarine, DTC

Primary Target: nAch
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505145
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Aperçu

Replacement Information

Tableau de caractéristiques principal

CAS #Empirical Formula
57-94-3C₃₇H₄₂Cl₂N₂O₆

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      Description
      OverviewA potent competitive antagonist of nAChR (IC50 = 41 nM). Used as nondepolarizing muscle relaxants during electroshock treatments, in convulsive states, and as anesthesia adjuvant.
      Catalogue Number505145
      Brand Family Calbiochem®
      SynonymsNicotinic Acetylcholine Receptor Antagonist, (+)-Tubocurarine chloride, D-tubocurarine, DTC
      References
      ReferencesBowman, C., 2006. Br. J. Pharmacol. 147, S277.
      Wenningmann, I., et al. 2001. Mol. Pharmacol. 60, 790.
      Pederson, X., 1990. Proc. Natl. Acad. Sci. USA. 87, 2785.
      Product Information
      CAS number57-94-3
      FormWhite solid
      Hill FormulaC₃₇H₄₂Cl₂N₂O₆
      Chemical formulaC₃₇H₄₂Cl₂N₂O₆
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetnAch
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 28

      Very toxic if swallowed.
      S PhraseS: 46

      If swallowed, seek medical advice immediately and show this container or label.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Toxic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Référence GTIN
      5051450001 04055977263374

      Documentation

      (+)-Tubocurarine Chloride - CAS 57-94-3 - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      Références bibliographiques

      Aperçu de la référence bibliographique
      Bowman, C., 2006. Br. J. Pharmacol. 147, S277.
      Wenningmann, I., et al. 2001. Mol. Pharmacol. 60, 790.
      Pederson, X., 1990. Proc. Natl. Acad. Sci. USA. 87, 2785.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision27-February-2018 JSW
      SynonymsNicotinic Acetylcholine Receptor Antagonist, (+)-Tubocurarine chloride, D-tubocurarine, DTC
      DescriptionA potent competitive antagonist of nAChR (IC50= 41 nM). Used as nondepolarizing muscle relaxants during electroshock treatments, in convulsive states, and as anesthesia adjuvant.
      FormWhite solid
      CAS number57-94-3
      Chemical formulaC₃₇H₄₂Cl₂N₂O₆
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityH₂O. Warming is required for complete solubilization.
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Toxic
      ReferencesBowman, C., 2006. Br. J. Pharmacol. 147, S277.
      Wenningmann, I., et al. 2001. Mol. Pharmacol. 60, 790.
      Pederson, X., 1990. Proc. Natl. Acad. Sci. USA. 87, 2785.