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530748 InSolution™ SRT1720, HCl - Calbiochem

A 25 mM (10 mg/650 µl) sterile-filtered solution of SRT1720, HCl in DMSO.

InSolution™ SRT1720, HCl - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: N-(2-(3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-quinolinecarboxamide, 4HCl;, Histone Acetyltransferase Inhibitor XI, p300/CBP Inhibitor IX, SRT1720, HCl InSolution™, HAT Inhibitor XI, SIRT3 Inhibitor II, Sirtuin-3 Inhibitor, SRT1720, HCl

Primary Target: SIRT3
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530748
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₂₅H₂₃N₇OS • xHCl

Pricing & Availability

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      		 Glass bottle 10 mg
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      Description
      OverviewAn enhanced aqueous soluble version of SRT1720 (Cat. No. 567860).

      Please note that the molecular weight for this compound is batch-specific due to variable water content.
      Catalogue Number530748
      Brand Family Calbiochem®
      SynonymsN-(2-(3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-quinolinecarboxamide, 4HCl;, Histone Acetyltransferase Inhibitor XI, p300/CBP Inhibitor IX, SRT1720, HCl InSolution™, HAT Inhibitor XI, SIRT3 Inhibitor II, Sirtuin-3 Inhibitor, SRT1720, HCl
      References
      ReferencesBaur, J.A., et al. 2012. Nat. Rev. Drug Discov. 11, 443.
      Minor, R.K., et al. 2011. Sci. Rep. 1, 70.
      Huber, J.L., et al. 2010. Future Med. Chem. 2, 1751.
      Pacholec, M., et al. 2010. J. Biol. Chem. 285, 8340.
      Jin, L., et al. 2009. Protein Sci. 18, 514.
      Feige, J.N., et al. 2008. Cell Metab. 8, 347.
      Milne, J.C., et al. 2007. Nature 450, 712.
      Product Information
      FormLiquid
      FormulationA 25 mM (10 mg/650 µl) sterile-filtered solution of SRT1720, HCl (Cat. No. 567860) in DMSO.
      Hill FormulaC₂₅H₂₃N₇OS • xHCl
      Chemical formulaC₂₅H₂₃N₇OS • xHCl
      Hygroscopic Hygroscopic
      ReversibleY
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetSIRT3
      Secondary targetp300 HAT
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      5307480001 04055977242959

      Documentation

      InSolution™ SRT1720, HCl - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Baur, J.A., et al. 2012. Nat. Rev. Drug Discov. 11, 443.
      Minor, R.K., et al. 2011. Sci. Rep. 1, 70.
      Huber, J.L., et al. 2010. Future Med. Chem. 2, 1751.
      Pacholec, M., et al. 2010. J. Biol. Chem. 285, 8340.
      Jin, L., et al. 2009. Protein Sci. 18, 514.
      Feige, J.N., et al. 2008. Cell Metab. 8, 347.
      Milne, J.C., et al. 2007. Nature 450, 712.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision27-June-2014 JSW
      SynonymsN-(2-(3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-quinolinecarboxamide, 4HCl;, Histone Acetyltransferase Inhibitor XI, p300/CBP Inhibitor IX, SRT1720, HCl InSolution™, HAT Inhibitor XI, SIRT3 Inhibitor II, Sirtuin-3 Inhibitor, SRT1720, HCl
      DescriptionAn enhanced aqueous soluble version of SRT1720 (Cat. No. 567860).
      FormLiquid
      FormulationA 25 mM (10 mg/650 µl) sterile-filtered solution of SRT1720, HCl (Cat. No. 567860) in DMSO.
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₂₅H₂₃N₇OS • xHCl
      Purity≥98% by HPLC
      Storage Protect from light
      Avoid freeze/thaw
      ≤ -70°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesBaur, J.A., et al. 2012. Nat. Rev. Drug Discov. 11, 443.
      Minor, R.K., et al. 2011. Sci. Rep. 1, 70.
      Huber, J.L., et al. 2010. Future Med. Chem. 2, 1751.
      Pacholec, M., et al. 2010. J. Biol. Chem. 285, 8340.
      Jin, L., et al. 2009. Protein Sci. 18, 514.
      Feige, J.N., et al. 2008. Cell Metab. 8, 347.
      Milne, J.C., et al. 2007. Nature 450, 712.