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345832 Galectin-3C, Human, Recombinant, E. coli

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345832
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345832-100UG
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      Description
      OverviewRecombinant, human galectin-3 expressed in E. coli and subsequently cleaved with Clostridium histolyticum collagenase type VII to yield galectin-3C. The resulting galectin-3C is purified by affinity chromatography. Galectin-3C is a truncated form of galectin-3 that contains the carbohydrate binding domain but lacks the 107 amino acids at the N-terminus of galectin-3. It is suggested to play a key role in autoimmune diseases, allergic reactions, inflammation, tumor cell metastasis, atherosclerosis, and diabetes.
      Catalogue Number345832
      Brand Family Calbiochem®
      References
      ReferencesHoyer K.K., et al. 2004. Am. J. Pathol. 164, 893.
      John C.M., et al. 2003. Clin. Cancer Res. 9, 2374.
      Iurisci, I., et al. 2000. Clin Cancer Res 6, 1389.
      Van Den Brule, F. A., et al. 2000. Int. J. Cancer 89, 361.
      Inohara, H. 1999. Cancer 85, 2475.
      Nakamura, M., et al. 1999. Int. J. Oncol. 15, 143.
      Idikio, H., et al. 1998. Int. J. Oncol. 12, 1287.
      Ochieng, J., et al. 1998. Biochim. Biophys. Acta. 1379 97.
      Castronovo, V., et al. 1996. J. Pathol. 179, 43.
      Liu, F.T., et al. 1996. Biochemistry 35 6073.
      Schoeppner, H. L., et al. 1995. Cancer 75, 2818.
      Massa, S.M., et al. 1993. Biochemistry 32, 260.
      Oda, Y., et al. 1991. Gene 99, 279.
      Product Information
      FormLyophilized
      FormulationLyophilized from deionized water, 2µg lactose/µg lectin.
      Quality LevelMQ100
      Biological Information
      Purity≥95% by SDS-PAGE
      Physicochemical Information
      ContaminantsEndotoxin: ≤ 1 EU/µg protein
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions (in the presence of a molar excess of lactose) are stable for up to 4 months at -20°C. For use in carbohydrate binding assays the solution should be dialyzed to remove the lactose stabilizer.
      Global Trade Item Number
      Catalogue Number GTIN
      345832-100UG 04055977214352