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344911 Fura-2 LR/AM - CAS 172890-84-5 - Calbiochem

A cell-permeable acetoxymethyl (AM) derivative of FURA-PE3 with spectral properties similar to the parent compound.

Fura-2 LR/AM - CAS 172890-84-5 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Fura-2 Leakage Resistant (AM)

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344911
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
172890-84-5C₅₅H₆₃N₅O₂₉

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      Description
      OverviewA cell-permeable acetoxymethyl (AM) derivative of FURA-PE3 with spectral properties similar to the parent compound. Can be loaded into cells in a manner similar to FURA 2/AM. Hydrolysis by non-specific esterases traps the indicator in the cytosol. Compared to FURA-2, it is retained longer in the cell. Note: 1 set = 10 x 50 µg.
      Catalogue Number344911
      Brand Family Calbiochem®
      SynonymsFura-2 Leakage Resistant (AM)
      References
      ReferencesAbe, F., et al. 1995. Br. J. Pharmacol. 116, 3000.
      Vorndran, C., et al. 1995. Biophys. J. 69, 2114.
      Product Information
      CAS number172890-84-5
      ATP CompetitiveN
      FormLight yellow gum
      Hill FormulaC₅₅H₆₃N₅O₂₉
      Chemical formulaC₅₅H₆₃N₅O₂₉
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetCalcium Probes
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Emission max.
      Excitation max.
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      344911-1SET 04055977214932

      Documentation

      Fura-2 LR/AM - CAS 172890-84-5 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Fura-2 LR/AM - CAS 172890-84-5 - Calbiochem Certificates of Analysis

      TitleLot Number
      344911

      References

      Reference overview
      Abe, F., et al. 1995. Br. J. Pharmacol. 116, 3000.
      Vorndran, C., et al. 1995. Biophys. J. 69, 2114.

      Brochure

      Title
      Caspases and other Apoptosis Related Tools Brochure
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision14-October-2020 JSW
      SynonymsFura-2 Leakage Resistant (AM)
      DescriptionAn acetoxymethyl (AM) derivative of FURA-PE3 with spectral properties similar to the parent compound. Can be loaded into cells in a manner similar to FURA 2/AM (Cat. No. 344905). Hydrolysis by non-specific esterases traps the indicator in the cytosol. Spectral properties in the presence of low calcium concentrations (ex. 364 nm, em. 508 nm) differ from those during high calcium conditions (ex. 335 nm, em. 495 nm). Note: 1 set = 10 x 50 µg.
      FormLight yellow gum
      CAS number172890-84-5
      Chemical formulaC₅₅H₆₃N₅O₂₉
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (10 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Toxicity Standard Handling
      ReferencesAbe, F., et al. 1995. Br. J. Pharmacol. 116, 3000.
      Vorndran, C., et al. 1995. Biophys. J. 69, 2114.

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      Categories

      Life Science Research > Inhibitors and Biochemicals > Biochemicals > Dyes, Stains and Probes > Calcium Probes