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341283 Factor P, Human

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341283
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Overview

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341283-250UG
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      Plastic ampoule 250 μg
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      Description
      OverviewNative factor P from human serum. Glycoprotein found in blood plasma in dimeric, trimeric, and tetrameric forms with M.W. of 92 kDa, 138 kDa, and 184 kDa, respectively. Present in normal human serum at about 20 µg/ml. Regulatory protein of the alternative pathway of complement activation. Accelerates complement activation by binding to and stabilizing the alternative pathway C3 and C5 convertase enzymes.
      Catalogue Number341283
      Brand Family Calbiochem®
      SynonymsProperdin
      References
      ReferencesPangburn, M.K., et al. 1988. Methods Enzymol. 162, 639.
      Smith, C.A., et al. 1984. J. Biol. Chem. 259, 4582.
      Product Information
      FormLiquid
      FormulationIn PBS, pH 7.2.
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥90% by SDS-PAGE
      SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Physicochemical Information
      ContaminantsIgG, IgA, IgM, Factor I, Factor B, Factor H, C3, C4, or albumin (by Ouchterlony): ≤trace amounts
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      341283-250UG 04055977215595

      Documentation

      Factor P, Human SDS

      Title

      Safety Data Sheet (SDS) 

      Factor P, Human Certificates of Analysis

      TitleLot Number
      341283

      References

      Reference overview
      Pangburn, M.K., et al. 1988. Methods Enzymol. 162, 639.
      Smith, C.A., et al. 1984. J. Biol. Chem. 259, 4582.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision24-June-2008 RFH
      SynonymsProperdin
      DescriptionNative factor P from human serum. Glycoprotein found in circulating blood plasma in dimeric, trimeric, and tetrameric forms with M.W. of ~92 kDa, ~138 kDa, and ~184 kDa, respectively. Present in normal human serum at about 20 µg/ml. Regulatory protein of the alternative pathway of complement activation. Accelerates complement activation by binding to and stabilizing the alternative pathway C3 and C5 convertase enzymes.
      FormLiquid
      FormulationIn PBS, pH 7.2.
      SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Purity≥90% by SDS-PAGE
      ContaminantsIgG, IgA, IgM, Factor I, Factor B, Factor H, C3, C4, or albumin (by Ouchterlony): ≤trace amounts
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesPangburn, M.K., et al. 1988. Methods Enzymol. 162, 639.
      Smith, C.A., et al. 1984. J. Biol. Chem. 259, 4582.