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505026 DNQX Disodium Salt - CAS 2379-57-9 - Calbiochem

Overview

Key Spec Table

CAS #Empirical Formula
2379-57-9C₈H₂N₄O₆Na₂

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      Glass bottle 10 mg
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      Description
      OverviewA potent competitive antagonist selective for AMPA/kainate glutamate receptors (IC50 = 0.19-1.66 µM and 0.35 µM for AMPA and GluK2 receptors, respectively). Routinely used as a tool to distinguish the role of neurotransmissions mediated by AMPA/kainate and NMDA receptors in studying brain functions and disorders.
      Catalogue Number505026
      Brand Family Calbiochem®
      SynonymsAMPA Glutamate Receptor Antagonist, DNQX, Kainate Glutamate Receptor Antagonist, DNQX
      References
      ReferencesLee, S., et al. 2010. J. Neurophysiol. 103, 1728.
      Honor, T., et al. 1998. Science. 241, 701.
      Watkins, J., et al. 1990. Adv. Exp. Med. Biol. 268, 49.
      Davies, S., et al. 1990. Int. Rev. Neurobiol. 32, 28.
      Product Information
      CAS number2379-57-9
      FormDark brown solid
      Hill FormulaC₈H₂N₄O₆Na₂
      Chemical formulaC₈H₂N₄O₆Na₂
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetAMPA
      Primary Target IC<sub>50</sub>0.19 to 1.66 uM
      Secondary targetGluK2
      Purity≥99% by HPLC
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Global Trade Item Number
      Catalogue Number GTIN
      5050260001 04055977263336