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234610 Congo Red, High Purity - CAS 573-58-0 - Calbiochem

An amyloidophylic dye that specifically stains stacked β sheet aggregates.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 3,3ʹ-[(1,1ʹ-Biphenyl)-4,4ʹ-diylbis(azo)]bis(4-amino-1-naphthalenesulfonic Acid) 2Na

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234610
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Overview

Key Spec Table

CAS #Empirical Formula
573-58-0C₃₂H₂₂N₆O₆S₂ · 2Na

Pricing & Availability

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234610-500MG
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      Description
      OverviewAn amyloidophylic dye that specifically stains stacked β sheet aggregates. Useful for staining and visual detection of amyloid deposits. Does not bind to non-polymerized amyloid peptide. Inhibits the accumulation of the scrapie-associated, protease-resistant isoform of protein PrP without affecting the metabolism of the normal isoform. It is also shown to inhibit Pot1 Binding to Telomeric DNA.
      Catalogue Number234610
      Brand Family Calbiochem®
      Synonyms3,3ʹ-[(1,1ʹ-Biphenyl)-4,4ʹ-diylbis(azo)]bis(4-amino-1-naphthalenesulfonic Acid) 2Na
      References
      ReferencesAltschuler, S.E., et al. 2012. Biochemistr in press.
      Khurana, R., et al. 2001. J. Biol. Chem. 276, 22715.
      Fezoui, Y., et al. 2000. Amyloid 7, 166.
      Fezoui, Y., et al. 2000. Nat. Struct. Biol. 7, 1095.
      Kramport, M., et al. 2000. Chem. Biol. 7, 855.
      Kuner, P., et al. 2000. J. Biol. Chem. 275, 1673.
      Caspi, S., et al. 1998. J. Biol. Chem. 273, 3484.
      Caughey, B., and Race, A.E. 1992. J. Neurochem. 59, 768.
      Taylor, D.L., et al. 1974. J. Histochem. Cytochem. 22, 1105.
      Product Information
      CAS number573-58-0
      ATP CompetitiveN
      FormRust crystalline solid
      Hill FormulaC₃₂H₂₂N₆O₆S₂ · 2Na
      Chemical formulaC₃₂H₂₂N₆O₆S₂ · 2Na
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetAn amyloidophylic dye that specifically stains stacked β sheet aggregates
      Purity≥75% (dye content)
      Physicochemical Information
      Cell permeableN
      Safety Information according to GHS
      RTECSQK1400000
      Safety Information
      S PhraseS: 25

      Avoid contact with eyes.
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +15°C to +30°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at room temperature (20°C).
      Global Trade Item Number
      Catalogue Number GTIN
      234610-500MG 04055977199635