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CC118 Chicken Tenascin

Chicken Tenascin MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Positive Control, Cell Culture
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CC118
50 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Key Applications
      PC, CULT
      Description
      Catalogue NumberCC118
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionChicken Tenascin
      OverviewTenascin is a large glycoprotein that forms disulfide-linked hexamers. It is made up of repeated structural domains including EGF-like repeats, fibronectin type III repeats, and a region homologous to fibrinogen. Splice variants of tenascin differ in their number of fibronectin type III repeats. Tenascin is expressed in distinctive spatial and temporal patterns in most embryonic tissues at sites of tissue remodeling and cell migration. There is little expression of tenascin in adult tissues except, again, at sites of tissue remodeling and cell migration such as surrounding tumors, in healing wounds, and in branching or damaged blood vessels. Tenascin binds to several cell-surface receptors and mediates cell-substrate adhesion. Nevertheless, tenascin is frequently referred to as an anti-adhesion molecule because for a variety of cell types the presence of tenascin inhibits adhesion to other ECM proteins present. This effect occurs because the binding of tenascin to certain receptors inhibits cell spreading and thereby blocks the stabilization of adhesion that results from cell preading in vitro assays.
      Alternate Names
      • Cytotactin
      • Tenascin-C
      References
      Product Information
      PresentationProvided as a liquid in PBS, containing no preservatives.
      Quality LevelMQ100
      Applications
      Key Applications
      • Positive Control
      • Cell Culture
      Biological Information
      Concentration0.5 mg/mL
      PurityIsolated from embryonic chicken brains by chromatographic methods. Contains three characteristic polypeptide chains (220, 200, and 190 kDa) that migrate on SDS gels as a high molecular weight multimer under non-reducing conditions.
      SourcePurified from embrionic chicken brains.
      UniProt Number
      Stem Cell Type
      • Mouse Embryonic Stem Cells
      • Mesenchymal Stem Cells
      • Neural Stem Cells
      • Hematopoietic Stem Cells
      • Epithelial Cells
      • Pancreatic Stem Cells
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C for up to 12 months. Avoid repeated freeze/thaw.
      Packaging Information
      Material Size50 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      CC118 04053252678813

      Documentation

      Chicken Tenascin SDS

      Title

      Safety Data Sheet (SDS) 

      Chicken Tenascin Certificates of Analysis

      TitleLot Number
      CHICKEN TENASCIN - 3897690 3897690
      CHICKEN TENASCIN -2615117 2615117
      CHICKEN TENASCIN PURIFIED PROTEIN 2935439
      CHICKEN TENASCIN PURIFIED PROTEIN 2907172
      CHICKEN TENASCIN PURIFIED PROTEIN - 4030510 4030510
      Chicken Tenascin Purified Protein 2472937

      References

      Reference overviewPub Med ID
      A detailed structural model of cytotactin: protein homologies, alternative RNA splicing, and binding regions
      Jones, F S, et al
      Proc Natl Acad Sci USA, 86:1905-9 (1989)  1989

      		2467292 2467292
      Two contrary functions of tenascin: dissection of the active sites by recombinant tenascin fragments.
      Spring, J, et al.
      Cell, 59: 325-34 (1989)  1989

      Show Abstract       		2478295 2478295