Millipore Sigma Vibrant Logo

219372 Cathepsin G Inhibitor I - CAS 429676-93-7 - Calbiochem

Cathepsin G Inhibitor I, CAS 429676-93-7, is a potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G (IC50 = 53 nM and Ki = 63 nM).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: cathepsin G
View Products on Sigmaaldrich.com
219372
View Pricing & Availability

Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
429676-93-7C₃₆H₃₃N₂O₆P

Pricing & Availability

Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
219372-1MG
Retrieving availability...
—
Fulfillment and delivery delayed Fulfillment and delivery delayed
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      		 Plastic ampoule 1 mg
      Retrieving price...
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
       
      —
      Request Pricing
      		 —
      219372-5MG
      Retrieving availability...
      —
      Fulfillment and delivery delayed Fulfillment and delivery delayed
      In Stock 
      Discontinued
      Limited Quantities Available
      Availability to be confirmed
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          		 Glass bottle 5 mg
          Retrieving price...
          Price could not be retrieved
          Minimum Quantity is a multiple of
          Maximum Quantity is
          Upon Order Completion More Information
          You Saved ()
           
          —
          Request Pricing
          		 —
          Description
          OverviewA potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G [IC50 = 53 nM and Ki = 63 nM]. Weakly inhibits chymotrypsin (Ki = 1.5 µM) and poorly inhibits thrombin, factor Xa, factor IXa, plasmin, trypsin, tryptase, proteinase 3, and human leukocyte elastase (IC50 > 100 µM).
          Catalogue Number219372
          Brand Family Calbiochem®
          References
          ReferencesGreco, M.N., et al. 2002. J. Am. Chem. Soc. 124, 3810.
          Product Information
          CAS number429676-93-7
          ATP CompetitiveN
          FormWhite solid
          Hill FormulaC₃₆H₃₃N₂O₆P
          Chemical formulaC₃₆H₃₃N₂O₆P
          ReversibleY
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          ApplicationCathepsin G Inhibitor I, CAS 429676-93-7, is a potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G (IC50 = 53 nM and Ki = 63 nM).
          Biological Information
          Primary Targetcathepsin G
          Primary Target IC<sub>50</sub>53 nM
          Primary Target K<sub>i</sub>63 nM for cathepsin G
          Purity≥98% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Catalogue Number GTIN
          219372-1MG 04055977202267
          219372-5MG 04055977202274

          Documentation

          Cathepsin G Inhibitor I - CAS 429676-93-7 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          Cathepsin G Inhibitor I - CAS 429676-93-7 - Calbiochem Certificates of Analysis

          TitleLot Number
          219372

          References

          Reference overview
          Greco, M.N., et al. 2002. J. Am. Chem. Soc. 124, 3810.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision05-April-2011 RFH
          DescriptionA potent, selective, reversible, and competitive non-peptide inhibitor of cathepsin G (IC50 = 53 nM and Ki = 63 nM). Weakly inhibits chymotrypsin (Ki = 1.5 µM) and does not have any significant inhibitory effect on thrombin, factor Xa, factor IXa, plasmin, trypsin, tryptase, proteinase 3, and human leukocyte elastase (IC50 > 100 µM).
          FormWhite solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number429676-93-7
          Chemical formulaC₃₆H₃₃N₂O₆P
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityDMSO (5 mg/ml) or Methanol
          Storage Protect from light
          -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesGreco, M.N., et al. 2002. J. Am. Chem. Soc. 124, 3810.