400012 Sigma-AldrichCaspase-1 Inhibitor II - CAS 178603-78-6 - Calbiochem
Caspase-1 Inhibitor II, CAS 178603-78-6, is a cell-permeable, irreversible inhibitor of caspase-1 (Ki = 760 pM), caspase-4, and caspase-5.
More>> Caspase-1 Inhibitor II, CAS 178603-78-6, is a cell-permeable, irreversible inhibitor of caspase-1 (Ki = 760 pM), caspase-4, and caspase-5. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: IL-1β Converting Enzyme (ICE) Inhibitor II, Ac-YVAD-CMK
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Overview
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Key Spec Table
| CAS # | Empirical Formula |
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| 178603-78-6 | C₂₄H₃₃ClN₄O₈ |
Pricing & Availability
| Catalogue Number | Availability | Packaging | Qty/Pack | Price | Quantity | |
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| 400012-5MG |
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Plastic ampoule | 5 mg |
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| Product Information | |
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| CAS number | 178603-78-6 |
| ATP Competitive | N |
| Form | White solid |
| Hill Formula | C₂₄H₃₃ClN₄O₈ |
| Chemical formula | C₂₄H₃₃ClN₄O₈ |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications | |
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| Application | Caspase-1 Inhibitor II, CAS 178603-78-6, is a cell-permeable, irreversible inhibitor of caspase-1 (Ki = 760 pM), caspase-4, and caspase-5. |
| Biological Information | |
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| Primary Target | caspase-1 |
| Primary Target K<sub>i</sub> | 760 pM against caspase-1 |
| Purity | ≥95% by HPLC |
| Physicochemical Information | |
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| Cell permeable | Y |
| Peptide Sequence | Ac-Tyr-Val-Ala-Asp-CMK |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information |
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| Specifications |
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| Global Trade Item Number | |
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| Catalogue Number | GTIN |
| 400012-5MG | 07790788049928 |
Documentation
Caspase-1 Inhibitor II - CAS 178603-78-6 - Calbiochem SDS
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Caspase-1 Inhibitor II - CAS 178603-78-6 - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 400012 |
References
| Reference overview |
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| Brenner, B., et al. 1998. Cell Death Differ. 5, 29. Garcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608. Hilbi, H., et al. 1998. J. Biol. Chem. 273, 32895. Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. Schlegel, J., et al. 1996. J. Biol. Chem. 271, 1841. Enari, M., et al. 1995. Nature 375, 78. Walker, N.P.C., et al. 1994. Cell 78, 343. Thornberry, N., et al. 1992. Nature 356, 768. |
Brochure
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| Caspases and other Apoptosis Related Tools Brochure |
Citations
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| Data Sheet | ||||||||||||||||||||||||||||||||
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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