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MABC94 Anti-Sphingosine 1-phosphate receptor 1 (S1P1) Antibody, clone 8B7.1

This Anti-Sphingosine 1-phosphate receptor 1 (S1P1) Antibody, clone 8B7.1 is validated for use in Western Blotting, IHC for the detection of Sphingosine 1-phosphate receptor 1 (S1P1).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: GPCR, cAMP/cGMP & Calcium Signaling Gene Symbol: S1PR1, CHEDG1, EDG1 UniProt Number: P21453
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MABC94
100 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWB, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABC94
      DescriptionAnti-Sphingosine 1-phosphate receptor 1 (S1P1) Antibody, clone 8B7.1
      Alternate Names
      • Sphingosine 1-phosphate receptor 1
      • S1P receptor 1
      • S1P1
      • Endothelial differentiation G-protein coupled receptor 1
      • Sphingosine 1-phosphate receptor Edg-1
      • S1P receptor Edg-1
      • CD363
      Background InformationSphingosine 1-phosphate receptor 1(S1PR1 or S1P1), otherwise known as EDG1, is a G-protein coupled receptor which is activated by lysosphingolipid sphingosine 1-phosphate (S1P) and lysophosphatidic acid (LPA). It is coupled to Gi-protein and MAP kinase signaling pathways, and may cooperate with other S1P receptors to regulate various cellular processes such as differentiation, actin remodeling, and migration. S1P1 is expressed in epithelial cells, fibroblasts, melanocytes, and smooth muscle cells.
      References
      Product Information
      FormatPurified
      Control
      • Mouse brain tissue lysate
      PresentationPurified mouse monoclonal IgG2a supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Sphingosine 1-phosphate receptor 1 (S1P1) Antibody, clone 8B7.1 is validated for use in Western Blotting, IHC for the detection of Sphingosine 1-phosphate receptor 1 (S1P1).
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesWestern Blot Analysis: A 1:500 dilution from a representative lot detected Sphingosine 1-phosphate receptor 1 (S1P1) in human brain tissue lysate.

      Immunohistochemistry Analysis: A 1:300 dilution from a representative lot detected Sphingosine 1-phosphate receptor 1 (S1P1) in rat choroid plexus tissue.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to mouse Sphingosine 1-phosphate receptor 1 (S1P1).
      Clone8B7.1
      HostMouse
      IsotypeIgG2a
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • S1PR1
      • CHEDG1
      • EDG1
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~40 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in mouse brain tissue lysate.

      Western Blot Analysis: A 1:1,000 diluiton of this antibody detected Sphingosine 1-phosphate receptor 1 (S1P1) in 10 µg of mouse brain tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABC94 04053252694240

      Documentation

      Anti-Sphingosine 1-phosphate receptor 1 (S1P1) Antibody, clone 8B7.1 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Sphingosine 1-phosphate receptor 1 (S1P1) Antibody, clone 8B7.1 Certificates of Analysis

      TitleLot Number
      Anti-Sphingosine 1-phosphate -2550060 2550060
      Anti-Sphingosine 1-phosphate -2794956 2794956
      Anti-Sphingosine 1-phosphate receptor 1 (S1P1), clone 8B7.1 - 2391198 2391198
      Anti-Sphingosine 1-phosphate receptor 1 (S1P1), clone 8B7.1 - 2159660 2159660
      Anti-Sphingosine 1-phosphate receptor 1 (S1P1), clone 8B7.1 - 2219401 2219401
      Anti-Sphingosine 1-phosphate receptor 1 (S1P1), clone 8B7.1 - 2309338 2309338
      Anti-Sphingosine 1-phosphate receptor 1 (S1P1), clone 8B7.1 - 3388466 3388466
      Anti-Sphingosine 1-phosphate receptor 1 (S1P1), clone 8B7.1 - 3734542 3734542
      Anti-Sphingosine 1-phosphate receptor 1 (S1P1), clone 8B7.1 - 3836590 3836590
      Anti-Sphingosine 1-phosphate receptor 1 (S1P1), clone 8B7.1 - 3942155 3942155
      Show more

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies