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AB9610-AF488 Anti-Olig-2 Antibody, Alexa Fluor® 488 Conjugate

Anti-Olig-2 Antibody, Alexa Fluor® 488 Conjugate is an antibody against Olig-2 for use in Immunofluorescence.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Transcription Factors Gene Symbol: Olig2, Bhlhb1 UniProt Number: Q9EQW6
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AB9610-AF488
100 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RIFRbAlexaFluor®488Polyclonal Antibody
      Description
      Catalogue NumberAB9610-AF488
      DescriptionAnti-Olig-2 Antibody, Alexa Fluor® 488 Conjugate
      Alternate Names
      • Oligodendrocyte transcription factor 2
      • bHLHe19
      • Olig-2
      • Oligo2
      • RACK17
      • RK17
      Background InformationOligodendrocyte transcription factor 2 (UniProt Q9EQW6; also known as bHLHe19, Olig-2, Oligo2, RACK17, RK17) is encoded by the Olig2 (also known as Bhlhb1) gene (Gene ID 50913) in murine species. Olig2 is a basic helix-loop-helix (bHLH) transcription factor expressed in a spinal cord ventricular zone domain where it mediates the sequential generation of motoneurons and oligodendrocytes during embryogenesis. Olig2 also functions as an anti-neurogenic factor in pMN progenitors at early time points to sustain the cycling progenitor pool. The anti-neurogenicity of Olig2 is also responsible for its role in tumorigenesis, especially in brain tumors and leukemia. Due to its expression in glioblastoma and other diffuse gliomas, Olig2 is a useful diagnostic marker of these brain tumors.
      Product Information
      FormatAlexaFluor®488
      PresentationPurified rabbit polyclonal antibody conjugate in PBS with 15 mg/mL BSA and 0.1 % sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Olig-2 Antibody, Alexa Fluor® 488 Conjugate is an antibody against Olig-2 for use in Immunofluorescence.
      Key Applications
      • Immunofluorescence
      Application NotesThe unconjugated antibody (Cat. No. AB9610) is shown to be suitable also for Western blotting, immunocytochemistry, immunohistochemistry, and immunoprecipitation applications.
      Biological Information
      ImmunogenRecombinant mouse Olig-2.
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      SpecificityThe unconjugated antibody (Cat. No. AB9610) recognizes the ~32 kDa Olig-2 protein by Western blotting.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • Olig2
      • Bhlhb1
      Purification MethodAmmonium Sulfate
      UniProt Number
      Molecular Weight~32 kDa observed.
      Product Usage Statements
      Quality AssuranceEvaluated by Immunofluorescence in mouse brain tissue.

      Immunofluorescence Analysis: A 1:50-100 dilution of this antibody detected Olig-2 in mouse brain tissue sections.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Global Trade Item Number
      Catalogue Number GTIN
      AB9610-AF488 04055977333664