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171601 Amyloid Precursor Protein β-Secretase Inhibitor - Calbiochem

The Amyloid Precursor Protein β-Secretase Inhibitor controls the biological activity of Amyloid Precursor Protein β-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: KTEETSEVN(stat)VAEF

Primary Target: APP
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171601
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₇₃H₁₁₈N₁₆O₂₇

Pricing & Availability

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171601-500UG
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      		 Plastic ampoule 500 μg
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      Description
      OverviewA potent inhibitor of the amyloid precursor protein (APP) β-secretase (IC50 = 30 nM).
      Catalogue Number171601
      Brand Family Calbiochem®
      SynonymsKTEETSEVN(stat)VAEF
      References
      ReferencesSinha, S., et al. 1999. Nature 402, 537.
      Product Information
      ATP CompetitiveN
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₇₃H₁₁₈N₁₆O₂₇
      Chemical formulaC₇₃H₁₁₈N₁₆O₂₇
      Hygroscopic Hygroscopic
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetAPP
      Primary Target IC<sub>50</sub>30 nM against amyloid precursor protein (APP) β-secretase
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide SequenceH-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Stat-Val-Ala-Glu-Phe-OH [Stat = (3S,4S)-Statine]
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      171601-500UG 04055977207293

      Documentation

      Amyloid Precursor Protein β-Secretase Inhibitor - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Amyloid Precursor Protein β-Secretase Inhibitor - Calbiochem Certificates of Analysis

      TitleLot Number
      171601

      References

      Reference overview
      Sinha, S., et al. 1999. Nature 402, 537.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision14-April-2008 RFH
      SynonymsKTEETSEVN(stat)VAEF
      DescriptionA potent inhibitor of the amyloid precursor protein (APP) β-secretase (IC50 = 30 nM).
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Chemical formulaC₇₃H₁₁₈N₁₆O₂₇
      Peptide SequenceH-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Stat-Val-Ala-Glu-Phe-OH [Stat = (3S,4S)-Statine]
      Purity≥98% by HPLC
      SolubilityAqueous Buffers (pH 7.5) (1 mg/ml).
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesSinha, S., et al. 1999. Nature 402, 537.