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454202 8-Methoxymethyl-3-isobutyl-1-methylxanthine - CAS 78033-08-6 - Calbiochem

A cell-permeable selective inhibitor of Ca2+-calmodulin-dependent phosphodiesterase (PDE I; IC₅₀ = 4 µM).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 8-Methoxymethyl-IBMX

Primary Target: PDE 1
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454202
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
78033-08-6C₁₂H₁₈N₄O₃

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454202-10MG
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      Description
      OverviewA cell-permeable selective inhibitor of Ca2+-calmodulin-dependent phosphodiesterase (PDE I; IC50 = 4 µM).
      Catalogue Number454202
      Brand Family Calbiochem®
      Synonyms8-Methoxymethyl-IBMX
      References
      ReferencesJackson, E.K., et al. 1997. J. Cardiovasc. Pharmacol. 30, 798.
      Ahn, H.S., et al. 1989. Biochem. Pharmacol. 38, 3331.
      Han, P., et al. 1989. J. Biol. Chem. 274, 22337.
      Product Information
      CAS number78033-08-6
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₁₂H₁₈N₄O₃
      Chemical formulaC₁₂H₁₈N₄O₃
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPDE 1
      Primary Target IC<sub>50</sub>4 µM against Ca2+-calmodulin-dependent phosphodiesterase (PDE I)
      Purity≥98% by TLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +15°C to +30°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      454202-10MG 04055977204742

      Documentation

      8-Methoxymethyl-3-isobutyl-1-methylxanthine - CAS 78033-08-6 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      8-Methoxymethyl-3-isobutyl-1-methylxanthine - CAS 78033-08-6 - Calbiochem Certificates of Analysis

      TitleLot Number
      454202

      References

      Reference overview
      Jackson, E.K., et al. 1997. J. Cardiovasc. Pharmacol. 30, 798.
      Ahn, H.S., et al. 1989. Biochem. Pharmacol. 38, 3331.
      Han, P., et al. 1989. J. Biol. Chem. 274, 22337.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision07-August-2008 RFH
      Synonyms8-Methoxymethyl-IBMX
      DescriptionA cell-permeable, selective inhibitor of Ca2+-calmodulin-dependent phosphodiesterase (PDE I, IC50 = 4 µM).
      FormWhite solid
      CAS number78033-08-6
      Chemical formulaC₁₂H₁₈N₄O₃
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityDMSO (5 mg/ml) or Ethanol (2 mg/ml)
      Storage +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesJackson, E.K., et al. 1997. J. Cardiovasc. Pharmacol. 30, 798.
      Ahn, H.S., et al. 1989. Biochem. Pharmacol. 38, 3331.
      Han, P., et al. 1989. J. Biol. Chem. 274, 22337.