g418 Search Results

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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

Normal plasma lipoproteins and fertility in gene-targeted mice homozygous for a disruption in the gene encoding very low density lipoprotein receptor.
The very low density lipoprotein (VLDL) receptor is a recently cloned member of the low density lipoprotein (LDL) receptor family that mediates the binding and uptake of VLDL when overexpressed in animal cells. Its sequence is 94% identical in humans and rabbits and 84% identical in humans and chickens, implying a conserved func...
Document Type:

Reference

Product Catalog Number:

RI-13K
Product Catalog Name:

Rat Insulin RIA
Binding of the radiolabeled glycine site antagonist [3H]MDL 105,519 to homomeric NMDA-NR1a receptors.
We have characterized the binding of [3H]MDL 105,519 ((E)-3-(2-phenyl-2-carboxyethenyl)-4,6-dichloro-1 H-indole-2-carboxylic acid), a NMDA receptor glycine recognition site antagonist, to homomeric NMDA subunit 1a (NR 1a) receptors. Chinese hamster ovary cells (CHO-K1) were transfected with the rat NR 1a gene and cell lines stab...
Document Type:

Reference

Product Catalog Number:

AP132A
Product Catalog Name:

Goat Anti-Rabbit IgG Antibody, Alkaline Phosphatase conjugate
Erythropoietin produced by genetic-modified NIH/3T3 fibroblasts enhances the survival of degenerating neurons.
Erythropoietin (EPO) has potent neuroprotective effects. The short-term delivery of high-dose EPO seemed to improve patients' neuromuscular functions; however, excessive EPO resulted in systematically high hematocrit and thrombotic risk. In our study, we established a cellular material for future in vivo studies of neurodeg...
Document Type:

Reference

Product Catalog Number:

Multiple
Product Catalog Name:

Multiple
Aggregates assembled from overexpression of wild-type alpha-synuclein are not toxic to human neuronal cells.
Filamentous alpha-synuclein (alpha-syn) aggregates form Lewy bodies (LBs), the neuropathologic hallmarks of Parkinson disease and related alpha-synucleinopathies. To model Lewy body-associated neurodegeneration, we generated transfectant 3D5 of human neuronal-type in which expression of human wild-type alpha-syn is regulated by...
Document Type:

Reference

Product Catalog Number:

AB5038P
Product Catalog Name:

Anti-Synuclein α Antibody
Translational read-through of the RP2 Arg120stop mutation in patient iPSC-derived retinal pigment epithelium cells.
Mutations in the RP2 gene lead to a severe form of X-linked retinitis pigmentosa. RP2 patients frequently present with nonsense mutations and no treatments are currently available to restore RP2 function. In this study, we reprogrammed fibroblasts from an RP2 patient carrying the nonsense mutation c.519Cgreater than T (p.R120X)...
Document Type:

Reference

Product Catalog Number:

MAB5428
Product Catalog Name:

Anti-Retinal Pigment Epithelium 65 Antibody
Identification, selection, and enrichment of cardiomyocyte precursors.
The large-scale production of cardiomyocytes is a key step in the development of cell therapy and tissue engineering to treat cardiovascular diseases, particularly those caused by ischemia. The main objective of this study was to establish a procedure for the efficient production of cardiomyocytes by reprogramming mesenchymal st...
Document Type:

Reference

Product Catalog Number:

Multiple
Product Catalog Name:

Multiple
METCAM/MUC18 augments migration, invasion, and tumorigenicity of human breast cancer SK-BR-3 cells.
Previous research has identified METCAM/MUC18, an integral membrane cell adhesion molecule (CAM) in the Ig-like gene super-family, as a promoter or a suppressor in the development of human breast cancer by MCF7, MDA-MB-231, and MDA-MB-468. To resolve these conflicting results we have investigated the role of this CAM in the prog...
Document Type:

Reference

Product Catalog Number:

AP162A
Product Catalog Name:

Rabbit Anti-Chicken IgG Antibody, Alkaline Phosphatase conjugate
Up-regulation of METCAM/MUC18 promotes motility, invasion, and tumorigenesis of human breast cancer cells.
Conflicting research has identified METCAM/MUC18, an integral membrane cell adhesion molecule (CAM) in the Ig-like gene super-family, as both a tumor promoter and a tumor suppressor in the development of breast cancer. To resolve this, we have re-investigated the role of this CAM in the progression of human breast cancer cells.T...
Document Type:

Reference

Product Catalog Number:

Multiple
Product Catalog Name:

Multiple
HumanKine® IL-1 beta, -VP1607010
Document Type:

Certificate of Analysis
Lot Number:

VP1607010

Product Catalog Number:

GF418
HumanKine® IL-1 beta, -VP1503031
Document Type:

Certificate of Analysis
Lot Number:

VP1503031

Product Catalog Number:

GF418

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g418

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Normal plasma lipoproteins and fertility in gene-targeted mice homozygous for a disruption in the gene encoding very low density lipoprotein receptor.

Binding of the radiolabeled glycine site antagonist [3H]MDL 105,519 to homomeric NMDA-NR1a receptors.

Erythropoietin produced by genetic-modified NIH/3T3 fibroblasts enhances the survival of degenerating neurons.

Aggregates assembled from overexpression of wild-type alpha-synuclein are not toxic to human neuronal cells.

Translational read-through of the RP2 Arg120stop mutation in patient iPSC-derived retinal pigment epithelium cells.

Identification, selection, and enrichment of cardiomyocyte precursors.

METCAM/MUC18 augments migration, invasion, and tumorigenicity of human breast cancer SK-BR-3 cells.

Up-regulation of METCAM/MUC18 promotes motility, invasion, and tumorigenesis of human breast cancer cells.

HumanKine® IL-1 beta, -VP1607010

HumanKine® IL-1 beta, -VP1503031

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