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65035 Trypsin Inhibitor, Soybean - CAS 9035-81-8 - Calbiochem

Trypsin Inhibitor, Soybean, CAS 9035-81-8, is a reversible inhibitor of trypsin that binds to trypsin in a stoichiometric, pH-dependent manner (Kd = 500 nM at pH 7.8).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: trypsin
65035
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Overview

Replacement Information

Key Spec Table

CAS #
9035-81-8

Products

Catalogue NumberPackaging Qty/Pack
65035-100MG Plastic ampoule 100 mg
65035-1GM Plastic ampoule 1 gm
Description
OverviewA reversible inhibitor of trypsin that binds to trypsin in a stoichiometric, pH-dependent manner (Kd = 500 nM at pH 7.8).
Catalogue Number65035
Brand Family Calbiochem®
References
ReferencesLilly, C.M., et al. 1993. J. Clin. Invest. 91, 235.
Uchino, T., et al. 1993. J. Biol. Chem. 268, 527.
Birk, Y. 1976. Methods Enyzmol. 45, 700.
Product Information
CAS number9035-81-8
Unit of DefinitionOne unit is defined as the amount of protein that will inhibit 1 unit of trypsin activity using BAEE as a substrate at 25°C, pH 7.6.
ATP CompetitiveN
FormOff-white lyophilized solid
Hygroscopic Hygroscopic
ReversibleY
Quality LevelMQ100
Applications
ApplicationTrypsin Inhibitor, Soybean, CAS 9035-81-8, is a reversible inhibitor of trypsin that binds to trypsin in a stoichiometric, pH-dependent manner (Kd = 500 nM at pH 7.8).
Biological Information
Primary Targettrypsin
Primary Target IC<sub>50</sub>Kd = 500 nM at pH 7.8 against trypsin
Specific Activity≥4000 units/mg protein
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Moisture Protect from moisture
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 1 week at 4°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
65035-100MG 07790788052164
65035-1GM 04055977184501

Documentation

Trypsin Inhibitor, Soybean - CAS 9035-81-8 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Trypsin Inhibitor, Soybean - CAS 9035-81-8 - Calbiochem Certificates of Analysis

TitleLot Number
65035

References

Reference overview
Lilly, C.M., et al. 1993. J. Clin. Invest. 91, 235.
Uchino, T., et al. 1993. J. Biol. Chem. 268, 527.
Birk, Y. 1976. Methods Enyzmol. 45, 700.

Citations

Title
  • Elizabeth A. Lipscomb, et al. (2005) The α6β4 integrin maintains the survival of human breast carcinoma cells in vivo. Cancer Research 65, 10970-10976.
    		•
    Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision02-October-2017 JSW
    DescriptionReversible inhibitor of trypsin that binds to trypsin in a stoichiometric, reversible and pH-dependent manner (Kd = 0.5 nM at pH 7.8). Also inhibits, to a lesser degree, chymotrypsin, kallikrein, plasmin, and other serine proteases.
    FormOff-white lyophilized solid
    Recommended reaction conditionsInactivates trypsin on an equal molar basis. To ensure complete inhibition of trypsin activity, a working concentration of soybean trypsin inhibitor should exceed that of trypsin by a factor of at least 2.
    CAS number9035-81-8
    Specific activity≥4000 units/mg protein
    Unit definitionOne unit is defined as the amount of protein that will inhibit 1 unit of trypsin activity using BAEE as a substrate at 25°C, pH 7.6.
    Solubility67 mM potassium phosphate, pH 7.6 (5 mg/ml)
    Storage Protect from moisture
    -20°C
    Hygroscopic
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 1 week at 4°C.
    Toxicity Standard Handling
    ReferencesLilly, C.M., et al. 1993. J. Clin. Invest. 91, 235.
    Uchino, T., et al. 1993. J. Biol. Chem. 268, 527.
    Birk, Y. 1976. Methods Enyzmol. 45, 700.
    Citation
  • Elizabeth A. Lipscomb, et al. (2005) The α6β4 integrin maintains the survival of human breast carcinoma cells in vivo. Cancer Research 65, 10970-10976.
    		•