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573102 STAT3 Inhibitor VI, S3I-201 - CAS 501919-59-1 - Calbiochem

573102
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Overview

Key Spec Table

CAS #Empirical Formula
501919-59-1C₁₆H₁₅NO₇S

Products

Catalogue NumberPackaging Qty/Pack
573102-10MG Plastic ampoule 10 mg
573102-25MG Plastic ampoule 25 mg
Description
OverviewA cell-permeable amidosalicylic acid compound that binds Stat3-SH2 domain and prevents Stat3 phosphorylation/activation, dimerization, DNA-binding, and Stat3-dependent transcription. Shown to arrest Stat3-dependent tumor growth both in cultures in vitro (effective conc. ≤100 µM) and in a murine xenograft model in vivo (5 mg/kg, i.v.). Also available as a 50 mM solution in DMSO (Cat. No. 573130).
Catalogue Number573102
Brand Family Calbiochem®
Synonyms2-Hydroxy-4-(((4-methylphenyl)sulfonyloxy)acetyl)amino)-benzoic acid, NSC 74859
References
ReferencesLin, L., et al. 2009. Oncogene, 28, 961.
Siddiquee, K., et al. 2007. Proc. Natl. Acad. Sci. USA 104, 7391.
Product Information
CAS number501919-59-1
FormLight beige solid
Hill FormulaC₁₆H₁₅NO₇S
Chemical formulaC₁₆H₁₅NO₇S
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Purity≥95% by HPLC
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Regulatory Review
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Catalogue Number GTIN
573102-10MG 04055977266429
573102-25MG 04055977266436