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554325 Resveratrol - CAS 501-36-0 - Calbiochem

554325
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Overview

Key Spec Table

CAS #Empirical Formula
501-36-0C₁₄H₁₂O₃

Products

Catalogue NumberPackaging Qty/Pack
554325-25MG Plastic ampoule 25 mg
Description
OverviewA phenolic product found in both grape skins and wines. Has antifungal, antitumor, and antioxidative properties. A specific inhibitor of cyclooxygenase-1 (COX-1; ED50 = 15 µM). Also inhibits the hydroxyperoxidase activity of COX-1 (ED50 = 3.7 µM). Strongly inhibits insoluble transthyretin (TTR) amyloid fibril formation. Inhibits phorbol ester-induced free radical formation in HL-60 cells (ED50 = 27 µM) and acts as an anti-mutagenic agent (ED50 = 15 µM) in TM677 cells treated with DMBA. Also a selective inhibitor of P450 1A1. Reported to activate sirtuins and promote the survival of eukaryotic cells.
Catalogue Number554325
Brand Family Calbiochem®
Synonymstrans-3,4ʹ,5-Trihydroxystilbene
References
ReferencesHowitz, K.T., et al. 2003. Nature 425, 191.
Lin, H.Y., et al. 2002. J. Urol. 168, 748.
Klabunde, T., et al. 2000. Nat. Struct. Biol. 7, 312.
Chun, Y.J., et al. 1999. Biochem. Biophys. Res. Commun. 262, 20.
Jang, M., et al. 1997. Science 275, 218.
Chen, C.K., et al. 1996. Gen. Pharmacol. 27, 363.
Product Information
CAS number501-36-0
ATP CompetitiveN
FormOff-white solid
Hill FormulaC₁₄H₁₂O₃
Chemical formulaC₁₄H₁₂O₃
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary TargetCOX-1
Primary Target IC<sub>50</sub>ED50 = 15 µM against COX-1
Purity≥98% by HPLC
Physicochemical Information
Cell permeableN
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Global Trade Item Number
Catalogue Number GTIN
554325-25MG 04055977193053