Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

FCABS165A6 Milli-Mark™ Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate

Milli-Mark Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate detects level of MAPK 1/2 (tERK) & has been published & validated for use in FC.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: MAP Kinases Gene Symbol: MAPK1, p38, ERK, P42MAPK, ERK2, p40, PRKM1, p41mapk, PRKM2, MAPK2, p42-MAPK, p41, ERK-2, ERT1 UniProt Number: P21708
FCABS165A6
100 tests  
Purchase on Sigma-Aldrich

Special Offers

Overview

Replacement Information

Special Offers

100% Performance Guaranteed

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HFCRbAlexaFluor®647Polyclonal Antibody
Description
Catalogue NumberFCABS165A6
Trade Name
  • Milli-Mark
DescriptionMilli-Mark™ Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate
Alternate Names
  • Extracellular signal-regulated kinase 1
  • ERK-1
  • Insulin-stimulated MAP2 kinase
  • Mitogen-activated protein kinase 1
  • MAP kinase 1
  • MAPK 1
  • p44-ERK1
  • ERT2
  • MAP kinase isoform p44
  • p44
  • MAPK
  • Microtubule-associated protein 2 kinase
  • MNK1
Background InformationThe extracellular signal-regulated kinases 1 and 2 (ERK1 and ERK2), also called MAPK1 and MAPK2, are members of the Mitogen Activated Protein Kinase (MAPK) family of proteins found in all eukaryotes. Because the 44 kDa ERK1 and the 42 kDa ERK2 are highly homologous and both function in the same protein kinase cascade, the two proteins are often referred to collectively as ERK1/2 or MAPK1/2. The MAPK1/2 signaling cascade has been shown to be a critical regulator of cell differentiation, cell physiology and neuronal function. Aberrant control of MAPK1/2 activity has been implicated in a variety of pathological conditions, including cancer and autoimmune diseases, and efficient study methods are in demand.
References
Product Information
FormatAlexaFluor®647
Control
  • Jurkat cells
PresentationPurified rabbit polyclonal antibody conjugated to Alexa Fluor 647 in PBS buffer with 15mg/mL BSA and 0.1% Sodium Azide
Quality LevelMQ100
Applications
ApplicationMilli-Mark Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate detects level of MAPK 1/2 (tERK) & has been published & validated for use in FC.
Key Applications
  • Flow Cytometry
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to rat MAPK 1/2 at the C-terminus.
EpitopeC-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityAntibody recognizes MAPK1/2. C-terminus.
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryKinase involved in intracellular signalling; component of Mapk signalling pathway [RGD]
Gene Symbol
  • MAPK1
  • p38
  • ERK
  • P42MAPK
  • ERK2
  • p40
  • PRKM1
  • p41mapk
  • PRKM2
  • MAPK2
  • p42-MAPK
  • p41
  • ERK-2
  • ERT1
Purification MethodProtein A Purfied
UniProt Number
UniProt SummaryFUNCTION: Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1. Phosphorylates heat shock factor protein 4 (HSF4) By similarity
Molecular Weight43 kDa Calculated
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by flow cytometry using Jurkat cells
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.
Packaging Information
Material Size100 tests
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
FCABS165A6 04053252411984

Documentation

Milli-Mark™ Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate SDS

Title

Safety Data Sheet (SDS) 

Milli-Mark™ Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate Certificates of Analysis

TitleLot Number
Milli-Mark Anti-MAPK 1/2 (tERK), Alexa Fluor#174; 647 Conjugate - 2197289 2197289
Milli-Mark Anti-MAPK 1/2 (tERK), Alexa Fluor#174; 647 Conjugate - NRG1772829 NRG1772829
Milli-Mark™ Anti-MAPK 1/2 (tERK), Alexa Fluor® 647 Conjugate 3063882
Milli-Mark™ Anti-MAPK 1/2 (tERK), Alexa Fluor® 647 Conjugate - 3173841 3173841
Milli-Mark™ Anti-MAPK 1/2 (tERK), Alexa Fluor® 647 Conjugate - 3981703 3981703
Milli-Mark™ Anti-MAPK 1/2 (tERK), Alexa Fluor® 647 Conjugate -2750262 2750262
Milli-Mark™ Anti-MAPK 1/2 (tERK), Alexa Fluor® 647 Conjugate - 2420521 2420521

Related Products & Applications

Related Products

Catalogue Number Description
ABS44 Anti-MAPK 1/2 Antibody

Product Families

Flow Cytometry Kits & Antibodies

Merck's Milli-Mark and FlowCellect brands include fluorescent conjugated antibodies and multiparameter kits for cellular analysis. Designed, optimized, and validated for flow.
Learn More >>

MAPK Antibodies, Proteins, Inhibitors, & Assays

Offering hundreds of premium quality antibodies, enzymes, activity assays, and small molecule inhibitors for MAPK signaling research
Learn More >>

Related Products By: Brand Facete

Milli-Mark™

Categories

Life Science Research > Antibodies and Assays > Primary Antibodies