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FCMAB187F Milli-Mark™ Anti-CD23-FITC Antibody, clone MHM6

Detect CD23 using this Milli-Mark Anti-CD23-FITC Antibody, clone MHM6 validated for use in FC.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology UniProt Number: P06734
FCMAB187F
100 tests  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HFCMFITCMonoclonal Antibody
Description
Catalogue NumberFCMAB187F
Trade Name
  • Milli-Mark
DescriptionMilli-Mark™ Anti-CD23-FITC Antibody, clone MHM6
Alternate Names
  • Low affinity immunoglobulin epsilon Fc receptor
  • Lymphocyte IgE receptor
  • Fc-epsilon-RII
  • BLAST-2
  • Immunoglobulin E-binding factor
  • C-type lectin domain family 4 member J
Background InformationCD23 is a 45 kDa type II membrane glycoprotein belonging to the C-type lectin family, and is identical to the low affinity IgE receptor (FceRII) (Kikutani, 1987; Aubry, 1987). CD23 is primarily expressed on B cells and monocytes including a strong expression on EBV-transformed B lymphoblasts (Sarfati, 1997; Sarfati, 1995). CD23 is also present on a large variety of other cells such as T cells, eosinophils, platelets, Langerhans cells, and a subset of thymic epithelial cells (Sarfati, 1995). However, CD23 is absent in a large number of normal non-lymphoid human tissues, such as, central nervous system, endocrine glands, gastrointestinal, respiratory, urinary, and female/male reproductive system, skin, bone, cartilage, connective tissue, muscles, peripheral nerves, vessels, mesothelium, synovium, placenta, and umbilical cord (Pallesen, 1987). Anti-CD23, MHM6, was included in the Second, Third, Fourth, and Fifth International Workshop and Conference on Human Leukocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with CD23 (Sarfati, 1995).
References
Product Information
FormatFITC
Control
  • human lymphocytes
PresentationPurified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
Quality LevelMQ100
Applications
ApplicationDetect CD23 using this Milli-Mark Anti-CD23-FITC Antibody, clone MHM6 validated for use in FC.
Key Applications
  • Flow Cytometry
Biological Information
ImmunogenEBV-transformed B-lymphoblastoid cells
CloneMHM6
HostMouse
SpecificityAntibody recognizes Human CD23 antigen.
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThe human leukocyte differentiation antigen CD23 (FCE2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor.
Purification MethodProtein A Purfied
UniProt Number
UniProt SummaryThis receptor has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
Molecular Weight 45 kDa (Kikutani, 1987; Aubry, 1987)
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by flow cytometry using human lymphocytes.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.
Packaging Information
Material Size100 tests
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
FCMAB187F 04053252480317

Documentation

Milli-Mark™ Anti-CD23-FITC Antibody, clone MHM6 SDS

Title

Safety Data Sheet (SDS) 

Milli-Mark™ Anti-CD23-FITC Antibody, clone MHM6 Certificates of Analysis

TitleLot Number
Milli-Mark Anti-CD23-FITC, clone MHM6 - NRG1774107 NRG1774107
Milli-Mark™ Anti-CD23-FITC, clone MHM6 3076929
Milli-Mark™ Anti-CD23-FITC, -2545764 2545764
Milli-Mark™ Anti-CD23-FITC, -2629030 2629030
Milli-Mark™ Anti-CD23-FITC, clone MHM6 - 2527062 2527062
Milli-Mark™ Anti-CD23-FITC, clone MHM6 - 2532651 2532651
Milli-Mark™ Anti-CD23-FITC, clone MHM6 - 3239842 3239842
Milli-Mark™ Anti-CD23-FITC, clone MHM6 - 3836578 3836578
Milli-Mark™ Anti-CD23-FITC, clone MHM6 - 3845731 3845731
Milli-Mark™ Anti-CD23-FITC, clone MHM6 - 3976068 3976068
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