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FCMAB177F Milli-Mark™ Anti-CD10-FITC Antibody, clone SS2/36

Milli-Mark Anti-CD10-FITC Antibody, clone SS2/36 detects level of CD10 & has been published & validated for use in FC.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology UniProt Number: P08473
FCMAB177F
100 tests  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HFCMFITCMonoclonal Antibody
Description
Catalogue NumberFCMAB177F
Trade Name
  • Milli-Mark
DescriptionMilli-Mark™ Anti-CD10-FITC Antibody, clone SS2/36
Alternate Names
  • Neprilysin
  • Neutral endopeptidase 24.11
  • Neutral endopeptidase (NEP)
  • Enkephalinase
  • Atriopeptidase
  • Common acute
  • ymphocytic leukemia antigen (CALLA)
Background InformationCD10 is a 100 kDa protein belonging to a family of type II transmembrane metalloproteases which also includes the leukocyte antigens CD13, CD26, CD73 and aminopeptidase. The gene encoding CD10 is located on chromosome 3. CD10 is a zinc-dependent enzyme and is thought to down-regulate cellular responses to peptide hormones (Barclay, 1997). On lymphoid cells, CD10 is expressed on immature T and B precursor cells but is lost as the cells reach maturation. CD10 is, however, re-expressed on proliferating B cells and mature neutrophils (Jones, 1997). Anti-CD10, SS2/36, was included in the Third International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with CD 10 (Majdic, 1987).
Product Information
FormatFITC
Control
  • PBMCs
PresentationPurified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
Quality LevelMQ100
Applications
ApplicationMilli-Mark Anti-CD10-FITC Antibody, clone SS2/36 detects level of CD10 & has been published & validated for use in FC.
Key Applications
  • Flow Cytometry
Biological Information
ImmunogenAcute lymphoblastic leukemia cells
CloneSS2/36
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityAntibody recognizes Human CD10 antigen.
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Purification MethodProtein A Purfied
UniProt Number
Molecular Weight 100 kDa (Barclay, 1997)
Product Usage Statements
Quality AssuranceEvaluated by flow cytometry using human PBMCs
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.
Packaging Information
Material Size100 tests
Global Trade Item Number
Catalogue Number GTIN
FCMAB177F 04053252421815