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474705 Mevastatin, Sodium Salt - Calbiochem

Carboxylate form of Mevastatin that is active in whole cells and in cell-free assays.

Mevastatin, Sodium Salt - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: HMG-CoA reductase
474705
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₂₃H₃₅O₆ · Na

Products

Catalogue NumberPackaging Qty/Pack
474705-5MG Plastic ampoule 5 mg
Description
OverviewCarboxylate form of Mevastatin (Cat. No. 474700) that is active in whole cells and in cell-free assays.
Catalogue Number474705
Brand Family Calbiochem®
References
ReferencesSugiyama, M., et al. 2000. Biochem. Biophys. Res. Commun. 271, 88.
Endo, A. 1992. J. Lipid Res. 33, 1569.
Product Information
ATP CompetitiveN
FormWhite to off-white solid
Hill FormulaC₂₃H₃₅O₆ · Na
Chemical formulaC₂₃H₃₅O₆ · Na
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
Biological Information
Primary TargetHMG-CoA reductase
Purity≥98% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
474705-5MG 04055977185423

Documentation

Mevastatin, Sodium Salt - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Mevastatin, Sodium Salt - Calbiochem Certificates of Analysis

TitleLot Number
474705

References

Reference overview
Sugiyama, M., et al. 2000. Biochem. Biophys. Res. Commun. 271, 88.
Endo, A. 1992. J. Lipid Res. 33, 1569.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision16-September-2020 JSW
DescriptionCarboxylate form of Mevastatin (Cat. No. 474700) that is active in whole cells and in cell-free assays. Mevastatin is an antibiotic that acts as a potent inhibitor of HMG-CoA reductase. Suppresses Ras farnesylation and inhibits myoblast fusion. Causes cell cycle arrest in late G1 phase. Mevastatin may also induce bone morphogenic protein-2 (BMP-2).
FormWhite to off-white solid
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₂₃H₃₅O₆ · Na
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityDMSO (30 mg/ml) or Ethanol (20 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesSugiyama, M., et al. 2000. Biochem. Biophys. Res. Commun. 271, 88.
Endo, A. 1992. J. Lipid Res. 33, 1569.