420135 Sigma-AldrichJNK Inhibitor VIII - CAS 894804-07-0 - Calbiochem
JNK Inhibitor VIII, CAS 894804-07-0, is a cell-permeable, ATP-competitive, reversible inhibitor of JNK (Ki = 2 nM, 4 nM and 52 nM for JNK1, 2 and 3, respectively).
More>> JNK Inhibitor VIII, CAS 894804-07-0, is a cell-permeable, ATP-competitive, reversible inhibitor of JNK (Ki = 2 nM, 4 nM and 52 nM for JNK1, 2 and 3, respectively). Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-dimethoxyphenyl)acetamide
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Overview
Products
| Catalogue Number | Packaging | Qty/Pack | |
|---|---|---|---|
| 420135-5MG | Plastic ampoule | 5 mg |
| References | |
|---|---|
| References | Vivanco, I., et al. 2007. Cancer Cell 11, 555. Szczepankiewicz, B. G., et al. 2006. J. Med. Chem. 49, 3563. |
| Product Information | |
|---|---|
| CAS number | 894804-07-0 |
| ATP Competitive | Y |
| Form | Brown solid |
| Hill Formula | C₁₈H₂₀N₄O₄ |
| Chemical formula | C₁₈H₂₀N₄O₄ |
| Reversible | Y |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications | |
|---|---|
| Application | JNK Inhibitor VIII, CAS 894804-07-0, is a cell-permeable, ATP-competitive, reversible inhibitor of JNK (Ki = 2 nM, 4 nM and 52 nM for JNK1, 2 and 3, respectively). |
| Biological Information | |
|---|---|
| Primary Target | JNK |
| Primary Target K<sub>i</sub> | 2 nM, 4 nM and 52 nM for JNK1, 2 and 3, respectively |
| Purity | ≥95% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | Y |
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
| Global Trade Item Number | |
|---|---|
| Catalogue Number | GTIN |
| 420135-5MG | 04055977187656 |