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GF426 HumanKine® IL-28B, Human Recombinant Xeno-Free

GF426
10 µg  
Purchase on Sigma-Aldrich

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Overview

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Key Spec Table

SourcePurity
HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.Product is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE.
Description
Catalogue NumberGF426
Trade Name
  • HumanKine®
DescriptionHumanKine® IL-28B, Human Recombinant Xeno-Free
Alternate Names
  • Interleukin-28B
  • IL28B
Background InformationIL-28B is a cytokine distantly related to type I interferons and the IL-10 family. IL-28A, IL-28B, and IL-29 are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
References
Product Information
Formulation
PresentationProduct is presented in PBS and filtered through a 0.2 micron filter before lyophilization.
Quality LevelMQ300
Applications
Biological Information
PurityProduct is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE.
SourceHumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.
UniProt Number
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceBioactivity assay: Determined by the dose dependent protection of the cytopathic effect on A549 cells (human lung
adenocarcinoma epithelial cell line) that were challenged with encephalomyocarditis (EMC) virus. ED50 is typically 0.1-1 ng/ml.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C for up to 4 months from date of receipt. Further dilutions should be made into appropriate buffer or medium to which protein has been added.
Packaging Information
Material Size10 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
GF426 04053252905933

Related Products & Applications

Product Families

Categories

Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors