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368059 Granzyme B Substrate II, Fluorogenic - CAS 219138-02-0 - Calbiochem

368059
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Overview

Products

Catalogue NumberPackaging Qty/Pack
368059-1MG Plastic ampoule 1 mg
368059-5MG Plastic ampoule 5 mg
Description
OverviewA fluorogenic substrate for the detection of granzyme B and caspase-8 activity. Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore.
Catalogue Number368059
Brand Family Calbiochem®
SynonymsZ-IETD-AFC, Caspase-8 Substrate II
References
ReferencesKarahashi, H., and Amano, F. 2000. Biol. Pharm. Bull. 23, 140.
Product Information
CAS number219138-02-0
ATP CompetitiveN
FormWhite lyophilized solid
Hill FormulaC₃₇H₄₂F₃N₅O₁₃
Chemical formulaC₃₇H₄₂F₃N₅O₁₃
ReversibleN
Quality LevelMQ100
Biological Information
Primary TargetFluorogenic substrate for the detection of granzyme B and caspase-8 activity
Purity≥97% by HPLC
Physicochemical Information
Cell permeableN
Emission max.
Excitation max.
Peptide SequenceZ-Ile-Glu-Thr-Asp-AFC
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Global Trade Item Number
Catalogue Number GTIN
368059-1MG 07790788049621
368059-5MG 04055977192179