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368056 Granzyme B Inhibitor IV - Calbiochem

368056
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Empirical Formula
C₂₂H₃₄N₄O₉

Products

Catalogue NumberPackaging Qty/Pack
368056-1MG Plastic ampoule 1 mg
Description
OverviewA reversible inhibitor of granzyme B and caspase-8.
Catalogue Number368056
Brand Family Calbiochem®
SynonymsAc-IEPD-CHO, Caspase-8 inhibitor III
References
ReferencesHarris, J.L., et al. 1998. J. Biol. Chem. 273, 27364.
Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.
Product Information
ATP CompetitiveN
FormWhite solid
Hill FormulaC₂₂H₃₄N₄O₉
Chemical formulaC₂₂H₃₄N₄O₉
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetgranzyme B
Purity≥97% by HPLC
Physicochemical Information
Cell permeableN
Peptide SequenceAc-Ile-Glu-Pro-Asp-CHO
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
368056-1MG 04055977192148

Documentation

Granzyme B Inhibitor IV - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Granzyme B Inhibitor IV - Calbiochem Certificates of Analysis

TitleLot Number
368056

References

Reference overview
Harris, J.L., et al. 1998. J. Biol. Chem. 273, 27364.
Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.

Brochure

Title
Caspases and other Apoptosis Related Tools Brochure
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision02-July-2008 RFH
SynonymsAc-IEPD-CHO, Caspase-8 inhibitor III
DescriptionA reversible inhibitor of Granzyme B that also inhibits caspase-8. Granzyme B is a protease involved in the induction of rapid target cell death by cytotoxic lymphocytes.
FormWhite solid
Chemical formulaC₂₂H₃₄N₄O₉
Peptide SequenceAc-Ile-Glu-Pro-Asp-CHO
Structure formulaStructure formula
Purity≥97% by HPLC
SolubilityDMSO (5 mg/ml)
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesHarris, J.L., et al. 1998. J. Biol. Chem. 273, 27364.
Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.