Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

102431 Chloroform

EMPROVE® ESSENTIAL

Chloroform MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: TCM, Trichloromethane, Methane trichloride, Methyl trichloride

CAS #: 67-66-3 EC Number: 200-663-8 Molar Mass: 119.38 g/mol Chemical Formula: CHCl₃ Hill Formula: CHCl₃
102431
Purchase on Sigma-Aldrich
Learn about the Emprove® Program

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar Mass
67-66-3200-663-8CHCl₃CHCl₃119.38 g/mol

Products

Catalogue NumberPackaging Qty/Pack
1024311000 Glass bottle 1 l
1024312500 Glass bottle 2.5 l
1024316025 Drum stainl. st. 25 l
1024316190 Drum stainl. st. 190 l
Description
Catalogue Number102431
SynonymsTCM, Trichloromethane, Methane trichloride, Methyl trichloride
DescriptionChloroform
References
Product Information
CAS number67-66-3
EC index number602-006-00-4
EC number200-663-8
Hill FormulaCHCl₃
Chemical formulaCHCl₃
Molar Mass119.38 g/mol
HS Code2903 13 00
Structure formula ImageStructure formula Image
Quality LevelMQ500
Applications
Biological Information
Physicochemical Information
Boiling point61 °C (1013 hPa)
Density1.49 g/cm3 (25 °C)
Melting Point-64 °C
Vapor pressure210 hPa (20 °C)
Solubility8.7 g/l
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Rat 695 mg/kg
LD 50 dermalLD50 Rabbit > 3980 mg/kg
Safety Information according to GHS
Hazard Pictogram(s) Hazard Pictogram(s)
Hazard Pictogram(s)
Hazard Statement(s)H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H331: Toxic if inhaled.
H336: May cause drowsiness or dizziness.
H351: Suspected of causing cancer.
H361d: Suspected of damaging the unborn child.
H372: Causes damage to organs through prolonged or repeated exposure if swallowed.
Precautionary Statement(s)P202: Do not handle until all safety precautions have been read and understood.
P301 + P312: IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of water.
P304 + P340 + P311: IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P313: IF exposed or concerned: Get medical advice/ attention.
Signal WordDanger
RTECSFS9100000
Storage class6.1D Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3 highly hazardous to water
Disposal2
Organic halogenated solvents and solutions of organic halogen-containing substances: For strongly contaminated or mixed halogenated solvents container B: Caution: Do not use aluminium containers; in addition, in the case of water-containing chlorinated waste materials do not use stainless-steel containers (danger of leaks caused by corrosion).
Safety Information
Categories of dangerharmful, irritant, carcinogenic, toxic for reproduction
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +30°C.
Packaging Information
Transport Information
Declaration (railroad and road) ADR, RIDUN 1888 , 6.1, III
Declaration (transport by air) IATA-DGRUN 1888 , 6.1, III
Declaration (transport by sea) IMDG-CodeUN 1888 , 6.1, III, Segregation Group: 10 (Liquid halogenated hydrocarbons)
Supplemental Information
Specifications
Purity (GC)99.0 - 99.4 % (w/w)
Identity (IR)conforms
Acidity or alkalinityconforms
Density (d 20 °C/ 4 °C)1.474 - 1.479
Density (d 20 °C/20 °C)1.479 - 1.482
Boiling range (60-62°C)≥ 95 % (v/v)
Chloride (Cl)conforms
Free chlorine (as Cl)conforms
Ethanol (GC)1.0 - 2.0 % (v/v)
Related substances (GC)≤ 1.0 % (v/v)
Bromochloromethane (GC)≤ 0.01 %
1,2-Dichloroethene (GC)≤ 0.05 %
Dichloromethane (GC)≤ 0.01 %
Carbon tetrachloride (GC)≤ 0.01 %
1,1,2-Trichloroethene (GC)≤ 0.01 %
Other residual solvents (ICH Q3C)excluded by manufacturing process
Aldehydesconforms
Foreign chlorine compoundsconforms
Matter discolored by H₂SO₄conforms
Evaporation residue≤ 0.0010 %
Water≤ 0.10 %
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities).
Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Stabilized with 1,0 - 2,0 % (v/v) ethanol
Global Trade Item Number
Catalogue Number GTIN
1024311000 04022536033358
1024312500 04022536033372
1024316025 04022536033402
1024316190 04022536905709

Documentation

Material Qualification Dossier

TitleVersion
7.0

Quality Management Dossier (Open Access)

Title

Operational Excellence Dossier

Title

Chloroform SDS

Title

Safety Data Sheet (SDS) 

Chloroform Certificates of Analysis

Product Number PackagingSpecificationLot Number
1024311000 Glass bottlePDF Specification Document
1024312500 Glass bottlePDF Specification Document
1024316025 Drum stainl. st.PDF Specification Document
1024316190 Drum stainl. st.PDF Specification Document

Certificates

Title