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14-689M Casein Kinase 2α2 Protein, active, 250 µg

Active, N-terminal 6His-tagged, recombinant, full length, human Casein Kinase 2α2, for use in Kinase Assays.

14-689M
250 µg  Also available in 10 μg size (cat#14-689) and in bulk (cat#14-689-K).
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue Number14-689M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionCasein Kinase 2α2 Protein, active, 250 µg
OverviewN-terminal 6His-tagged, recombinant, full length, human Casein Kinase 2α2
References
Product Information
Quality LevelMQ300
Applications
ApplicationActive, N-terminal 6His-tagged, recombinant, full length, human Casein Kinase 2α2, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Sourceexpressed by baculovirus in Sf21 cells
Entrez Gene Number
Gene Symbol
  • CSNK2A2
  • CK2A2
  • CSNK2A1
  • FLJ43934
Protein TargetCK2α2
Purification MethodNi2+/NTA-agarose
Target Sub-FamilyCMGC
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P19784 # Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.
SIZE: 350 amino acids; 41213 Da
SUBUNIT: Tetramer composed of an alpha chain, an alpha' and two beta chains. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation.
SIMILARITY: SwissProt: P19784 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily. & Contains 1 protein kinase domain.
Molecular Weight45.8kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation of casein kinase 2 substrate peptide
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditionsstable for 6 months at -70°C from date of shipment
Packaging Information
Material Size250 µg
Material PackageAlso available in 10 μg size (cat#14-689) and in bulk (cat#14-689-K).
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
14-689M 04053252925337

Documentation

Related Products & Applications

Alternative Packsize

Catalogue Number Description
14-689 Casein Kinase 2α2 Protein, active, 10 µg

Product Families

Kinase & Phosphatase Products

Millipore offers a large portfolio of Kinases, Phophatases, Substrates, Inhibitors, Kits, reagents & tools for Signaling research. See below for a list of these products, in multiple pack sizes.
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Categories

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases