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MABN663 Anti-STMN2 Antibody, clone L5/1

MABN663
100 µg  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, RWB, IHC, ICCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN663
DescriptionAnti-STMN2 Antibody, clone L5/1
Alternate Names
  • Stathmin-2
  • Superior cervical ganglion-10 protein
  • Protein SCG10
Background InformationStathmin-like 2 (STMN2) protein is a phospho-protein and functions in microtubule dynamics and signal transduction. Studies show STMN2 plays a regulatory role in neuronal growth and thought to be involved in osteogenesis. Reduced levels, i.e. reduction in expression, have been associated with Down's syndrome and Alzheimer's disease. Data also suggests that STMN2 may play a role in modulating membrane interaction with the cytoskeleton during neurite outgrowth.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect STMN using this mouse monoclonal antibody, Anti-STMN2 Antibody, clone L5/1 validated for use in western blotting, IHC & ICC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
  • Immunocytochemistry
Application NotesWestern Blotting Analysis: 0.5 µg/mL from a representative lot detected STMN2 in 10 µg of rat fetal brain (E16) tissue lysate.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected STMN2 in rat hippocampus tissue.
Immunocytochemistry Analysis: A representative lot detected STMN2 in cultured hippocampal neurons (Prof. J. Trimmer, University of Califnornia, Davis.).
Biological Information
ImmunogenLinear peptide corresponding to the C-terminus of rat STMN2.
EpitopeC-terminus
CloneL5/1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgG2bκ
Species Reactivity
  • Human
  • Rat
Species Reactivity NoteHuman, Rat. Predicted to react with Mouse based on 100% sequence homology.
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • Stmn2
  • Scg10
  • Scgn10
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~21 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in SH-SY-5Y cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected STMN2 in 10 µg of SH-SY-5Y cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABN663 04053252932885

Documentation

Anti-STMN2 Antibody, clone L5/1 SDS

Title

Safety Data Sheet (SDS) 

Anti-STMN2 Antibody, clone L5/1 Certificates of Analysis

TitleLot Number
Anti-STMN2, clone L5/1 - 3224586 3224586
Anti-STMN2, clone L5/1 - 3513652 3513652
Anti-STMN2, clone L5/1 - 3523945 3523945
Anti-STMN2, clone L5/1 - 3979960 3979960
Anti-STMN2, clone L5/1 - 4095354 4095354
Anti-STMN2, clone L5/1 - 4195015 4195015
Anti-STMN2, clone L5/1 - 4201277 4201277
Anti-STMN2, clone L5/1 - Q2299326 Q2299326
Anti-STMN2, clone L5/1 Monoclonal Antibody 3060088