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MABT106 Anti-Protein Spindly Antibody, clone 9D10.2

MABT106
100 µg  
Purchase on Sigma-Aldrich

Special Offers

Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
M, HICC, WBMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABT106
DescriptionAnti-Protein Spindly Antibody, clone 9D10.2
Alternate Names
  • Protein Spindly
  • hSpindly
  • Arsenite-related gene 1 protein
  • Coiled-coil domain-containing protein 99
  • Rhabdomyosarcoma antigen MU-RMS-40.4A
Background InformationProtein spindly, otherwise known as the coiled-coil domain-containing protein 99 (CCDC99), is a phosphoprotein that regulates mitosis. It interacts with the Rod/ZW10/Zwilch complex, and is involved in recruiting, docking, and alignment of motor protein dynein at mitotic kinetochores. Spindly may also be involved in checkpoint signaling and microtubule attachment.
References
Product Information
FormatPurified
Control
  • HEK293 cell lysate
PresentationPurified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect Protein Spindly using this Anti-Protein Spindly Antibody, clone 9D10.2 validated for use in ICC, Western Blotting.
Key Applications
  • Immunocytochemistry
  • Western Blotting
Application NotesImmunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Protein Spindly in HeLa and NIH/3T3.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human Protein Spindly.
Clone9D10.2
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgMκ
Species Reactivity
  • Mouse
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • CCDC99
UniProt Number
Molecular Weight~70 kDa observed. This protein is known to exist in two isoforms at 70 kDa and 56 kDa. An uncharacterized band may be observed at ~38 kDa in some cell lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in HEK293 cell lysate.

Western Blot Analysis: 0.1 µg/mL of this antibody detected Protein Spindly in 10 µg of HEK293 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABT106 04053252551130

Documentation

Anti-Protein Spindly Antibody, clone 9D10.2 SDS

Title

Safety Data Sheet (SDS) 

Anti-Protein Spindly Antibody, clone 9D10.2 Certificates of Analysis

TitleLot Number
Anti-Protein Spindly, clone 9D10.2 - 3948900 3948900
Anti-Protein Spindly, clone 9D10.2 - Q2050293 Q2050293
Anti-Protein Spindly, clone 9D10.2 -2771827 2771827
Anti-Protein Spindly, clone 9D10.2 Monoclonal Antibody 2993680
Anti-Protein Spindly, clone 9D10.2, Monoclonal Antibody 2833490
Anti-Protein Spindly, clone 9D10.2_2825460 2825460