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AB4344 Anti-LYAR Antibody (Ly1 Antibody reactive clone)

Anti-LYAR Antibody (Ly1 reactive clone) detects level of LYAR (Ly1 antibody reactive clone) & has been published & validated for use in WB.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Stem Cell Research Research Sub-Category: Immunoglobulins & Immunology, Pluripotent & Early Differentiation Gene Symbol: Lyar, LYAR UniProt Number: Q08288
AB4344
100 µL  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
MWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberAB4344
DescriptionAnti-LYAR Antibody (Ly1 Antibody reactive clone)
Alternate Names
  • Cell growth-regulating nucleolar protein
  • Protein expressed in male leptotene and zygotene spermatocytes 264
  • MLZ-264
Background InformationLYAR, also known as Ly1 antibody reactive clone, has been found to regulate the intracellular strength that is stimulated by both T and B cell antigen receptors. It is essential for immune tolerance and certain changes to its function could stimulate the development of autoreactivity. LYAR is important in the immunological synapse and functions to inhibit the T cell response. LYAR is highly expressed in indifferentiated embryonic stem cells and may be important in maintaining the stem cell identity.
Product Information
FormatAffinity Purified
Control
  • Mouse embryonic stem cell lysate
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-LYAR Antibody (Ly1 reactive clone) detects level of LYAR (Ly1 antibody reactive clone) & has been published & validated for use in WB.
Key Applications
  • Western Blotting
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to mouse LYAR.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Mouse
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • Lyar
  • LYAR
Purification MethodAffinity Purfied
UniProt Number
UniProt SummarySUBCELLULAR LOCATION: Nucleus › nucleolus

TISSUE SPECIFICITY: Very high levels in immature spermatocytes in testis. Expressed in ovary.

DEVELOPMENTAL STAGE: Expressed in testis and ovary at E15.5.

SEQUENCE SIMILARITIES: Contains 2 C2HC-type zinc fingers.
Molecular Weight~48 kDa observed
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in mouse embryonic stem cell lysate.

Western Blot Analysis: A 1:1,000 dilution of this antibody detected LYAR in 10 µg of mouse embryonic stem cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Global Trade Item Number
Catalogue Number GTIN
AB4344 04053252754197