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MABT27 Anti-LIBS2 epitope (Integrin beta3 subunit) Antibody, clone ab62

Anti-LIBS2 epitope (Integrin beta3 subunit) Antibody, clone ab62 is an antibody against LIBS2 epitope (Integrin beta3 subunit) for use in WB, FC.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Integrins Gene Symbol: LIBS2
MABT27
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, FCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABT27
DescriptionAnti-LIBS2 epitope (Integrin beta3 subunit) Antibody, clone ab62
Alternate Names
  • LIBS2 domain, Integrin, Integrin alphaVbeta3, LIBS2 epitiope
Background InformationThe integrin family of cell adhesion receptors consists of at least 16 membrane-associated heterodimers, composed of an alpha and beta subunit that associate in a non-covalent manner. The involvement of integrins in vascular proliferation, adhesion, and wound repair has been well documented. The adhesion receptor, integrin alphaVbeta3, appears to be selectively expressed on growing blood vessels and has been identified as a marker of angiogenic vascular tissue.
Clone Ab62 is a monoclonal antibody that specifically recognizes the LIBS2 epitope in the C-terminal region of the extracellular domain of the beta3 subunit (Wiberzbicka-Patynowski, I., et al. (1999). JBC. 274(53):37809-37814).
References
Product Information
FormatPurified
Control
  • Human platelets cell lysate
PresentationPurified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-LIBS2 epitope (Integrin beta3 subunit) Antibody, clone ab62 is an antibody against LIBS2 epitope (Integrin beta3 subunit) for use in WB, FC.
Key Applications
  • Western Blotting
  • Flow Cytometry
Application NotesFlow Cytometry Analysis: A previous lot was used by an independent laboratory in FC (Ginsberg, M., et al. (1990). Blood. 76:2017-2023.)
Biological Information
ImmunogenHuman GPIIa-IIIb purified from platelets
EpitopeLIBS2 epitope in the C-terminal region of the extracellular domain of the beta3 subunit of integrins.
Cloneab62
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityThis antibody recognizes the LIBS2 epitope in the C-terminal region of the extracellular domain of the beta3 subunit of integrins.
IsotypeIgG2aκ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Gene Symbol
  • LIBS2
Purification MethodProtein G Purified
Molecular Weight~110 kDa observed in human platelets.
Other MW bands may vary or may be observed depending on lysate used and if the LIBS2 epitope is present in other proteins.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in human platelets cell lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected LIBS2 domain of integrin beta3 subunit in 10 µg of human platelets cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABT27 04053252554360

Documentation

Anti-LIBS2 epitope (Integrin beta3 subunit) Antibody, clone ab62 SDS

Title

Safety Data Sheet (SDS) 

Anti-LIBS2 epitope (Integrin beta3 subunit) Antibody, clone ab62 Certificates of Analysis

TitleLot Number
Anti-LIBS2 epitope (Integrin beta3 subunit), clone ab62 - 2389002 2389002
Anti-LIBS2 epitope (Integrin beta3 subunit), clone ab62 - 1996244 1996244
Anti-LIBS2 epitope (Integrin beta3 subunit), clone ab62 - 2199673 2199673
Anti-LIBS2 epitope (Integrin beta3 subunit), clone ab62 - 2275634 2275634
Anti-LIBS2 epitope (Integrin beta3 subunit), clone ab62 - 2299594 2299594
Anti-LIBS2 epitope (Integrin beta3 subunit), clone ab62 - 3180447 3180447
Anti-LIBS2 epitope (Integrin beta3 subunit), clone ab62 - 3500964 3500964
Anti-LIBS2 epitope (Integrin beta3 subunit), clone ab62 - 3697391 3697391
Anti-LIBS2 epitope (Integrin beta3 subunit), clone ab62 - 3739736 3739736
Anti-LIBS2 epitope (Integrin beta3 subunit), clone ab62 - 3894079 3894079
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