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MABN498 Anti-GABA(A)R BETA 1 Protein Antibody, clone N96/55

MABN498
100 µg  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
R, MIHC, WBMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN498
DescriptionAnti-GABA(A)R BETA 1 Protein Antibody, clone N96/55
Alternate Names
  • Gamma-aminobutyric acid receptor subunit beta-1
  • GABA(A) receptor subunit beta-1
Background InformationGABA(A)R, beta-1 is a subunit of the GABA receptor. GABA receptors belong to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid or GABA is the major inhibitory neurotransmitter in the vertebrate brain. GABA mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. GABA receptors play an important role in transmembrane ion transport, excitability and synaptic transmission.
References
Product Information
FormatPurified
Control
  • Rat hippocampus tissue
PresentationPurified monoclonal mouse IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis GABA(A)R antibody is validated for use in IHC & WB for the detection of the GABA(A)R protein.
Key Applications
  • Immunohistochemistry
  • Western Blotting
Application NotesImmunohistochemistry Analysis: A 1:500 dilution from a representative lot detected GABA(A)R, BETA 1 Protein in rat olfactory lobe tissue.

Western Blot Analysis: A representative lot detected GABA(A)R, BETA 1 Protein in rat brain membrane tissue lysate.

Immunohistochemistry Analysis: A representative lot detected GABA(A)R, BETA 1 Protein in rat hippocampus tissue.
Biological Information
ImmunogenFusion protein corresponding to mouse GABA(A)R, BETA 1.
CloneN96/55
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityThis antibody does not cross react with GABA-A-R, Beta 2 Protein or GABA-A-R, Beta 3 Protein.
IsotypeIgG1κ
Species Reactivity
  • Rat
  • Mouse
Species Reactivity NoteDemonstrated to react with Rat and Mouse. Other homologies: Human (95% sequence homology).
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • Gabrb1
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~55 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunohistochemistry in rat hippocampus tissue.

Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected GABA(A)R, BETA 1 Protein in rat hippocampus tissue.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABN498 04053252850936

Documentation

Anti-GABA(A)R BETA 1 Protein Antibody, clone N96/55 SDS

Title

Safety Data Sheet (SDS) 

Anti-GABA(A)R BETA 1 Protein Antibody, clone N96/55 Certificates of Analysis

TitleLot Number
Anti-GABA(A)R, BETA 1 Protein, clone N96/55 - 3904654 3904654
Anti-GABA(A)R, BETA 1 Protein, clone N96/55 - Q2138465 Q2138465
Anti-GABA(A)R, BETA 1 Protein, clone N96/55 -2523224 2523224
Anti-GABA(A)R, BETA 1 Protein, clone N96/55 -2576413 2576413
Anti-GABA(A)R, BETA 1 Protein, clone N96/55 -2891029 2891029