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07-2274 Anti-FSP1/S100A4 Antibody

Detect the FSP1/S100A4 protein using this Anti-FSP1/S100A4 validated for use in WB & IHC.

Anti-FSP1/S100A4 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: GPCR, cAMP/cGMP & Calcium Signaling Gene Symbol: S100A4, CAPL, FSP1, 18A2, PEL98, P9KA, 42A, MTS1 UniProt Number: P07091
07-2274
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
M, HWB, IH(P)RbPurifiedPolyclonal Antibody
Description
Catalogue Number07-2274
DescriptionAnti-FSP1/S100A4 Antibody
Alternate Names
  • S100 calcium binding protein A4
  • S100 calcium-binding protein A4
  • fibroblast-specific protein-1
  • leukemia multidrug resistance associated protein
  • S100 calcium binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog)
  • malignant transformation suppression 1
  • S100 calcium-binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog)
  • Metastasin
  • Protein Mts1
  • Placental calcium-binding protein
  • Calvasculin
Background InformationFibroblast-specific protein-1 (FSP1)/S100A4 is a cytoplasmic calcium-binding protein belonging to the S100 superfamily of which at least 21 members have been identified so far. Researchers believe that FSP1/S1004A is highly expressed in fibroblasts (Iwano et al., 2001; Strutz et al., 1995), in epithelial and endothelial cells undergoing epithelial-mesenchymal transition (EMT) (Iwano et al., 2002; Zeisberg and Neilson, 2009), and epithelial cancer cells that complete a transition to a metastatic phenotype (Xue et al., 2003).
References
Product Information
FormatPurified
Control
  • NIH/3T3 cell lysate
PresentationPurified rabbit polyclonal containing PBS with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect the FSP1/S100A4 protein using this Anti-FSP1/S100A4 validated for use in WB & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
Application NotesWestern Blot Analysis: 1 µg/mL from a previous lot detected S100-A4 on 10 µg of HeLa cell lysate.
Biological Information
ImmunogenHistidine-tagged recombinant protein corresponding to mouse FSP1/S100-A4.
EpitopeUnknown
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
IsotypeIgG
Species Reactivity
  • Mouse
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • S100A4
  • CAPL
  • FSP1
  • 18A2
  • PEL98
  • P9KA
  • 42A
  • MTS1
Purification MethodProtein G Purified
UniProt Number
UniProt SummarySUBUNIT STRUCTURE: Homodimer. Interacts with PPFIBP1 in a calcium-dependent mode (by similarity).

TISSUE SPECIFICTY: Specifically expressed in different metastatic cells.

INDUCTION: The mRNA coding for this protein increases in abundance after serum stimulation of quiescent mouse fibroblasts.

SEQUENCE SIMILARITIES: Belongs to the S-100 family.

Contains 2 EF-hand domains.
Molecular Weight~ 12 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in NIH/3T3 cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected FSP1/S100-A4 on 10 µg of NIH/3T3 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
07-2274 04053252288197

Documentation

Anti-FSP1/S100A4 Antibody SDS

Title

Safety Data Sheet (SDS) 

Anti-FSP1/S100A4 Antibody Certificates of Analysis

TitleLot Number
Anti-FSP1/S100A4 3071579
Anti-FSP1/S100A4 - 2120074 2120074
Anti-FSP1/S100A4 - 2145109 2145109
Anti-FSP1/S100A4 - 2433484 2433484
Anti-FSP1/S100A4 - 2453239 2453239
Anti-FSP1/S100A4 - 1995599 1995599
Anti-FSP1/S100A4 - 2006939 2006939
Anti-FSP1/S100A4 - 2036120 2036120
Anti-FSP1/S100A4 - 2281694 2281694
Anti-FSP1/S100A4 - 2488825 2488825
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