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07-210 Anti-AKAP 150 Antibody

07-210
200 µL  
Purchase on Sigma-Aldrich

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Overview

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
RWBRbSerumPolyclonal Antibody
Description
Catalogue Number07-210
Brand Family Upstate
Trade Name
  • Upstate
DescriptionAnti-AKAP 150 Antibody
Product Information
FormatSerum
Presentation0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Quality LevelMQ100
Applications
ApplicationAnti-AKAP 150 Antibody is an antibody against AKAP 150 for use in WB.
Key Applications
  • Western Blotting
Biological Information
Immunogenpeptide corresponding to amino acids 428-449 of rat AKAP 150 (C-TTVGQAEEATVGQAEEATVGQA)
HostRabbit
SpecificityAKAP 150
IsotypeIgG
Species Reactivity
  • Rat
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThe A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment.
Gene Symbol
  • AKAP1
  • AKAP121
  • AKAP84-PEN
  • SAKAP84
  • PRKA1
  • D-AKAP-1
  • AKAP
  • D-AKAP1
  • AKAP149
  • MGC1807
  • AKAP84
  • S-AKAP84
Purification MethodAntiserum
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q92667 # Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane.
SIZE: 903 amino acids; 97342 Da
SUBCELLULAR LOCATION: Mitochondrion outer membrane (Potential).
TISSUE SPECIFICITY: AKAP149 is highly expressed in prostate and small intestine whereas S-AKAP84 is expressed in kidney, pancreas, liver, lung and brain. AKAP149 is also expressed in colon carcinoma.
DOMAIN:SwissProt: Q92667 RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.
SIMILARITY: Contains 1 KH domain. & Contains 1 Tudor domain.
Molecular Weight150kDa
Product Usage Statements
Quality Assuranceroutinely evaluated by immunoblot on a rat brain cytosolic preparation
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions2 years at -20°C
Packaging Information
Material Size200 µL
Global Trade Item Number
Catalogue Number GTIN
07-210 04053252738777