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344039 cFMS Receptor Inhibitor IV - CAS 959626-45-0 - Calbiochem

The cFMS Receptor Inhibitor IV, also referenced under CAS 959626-45-0, controls the biological activity of cFMS. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: 5-Cyano-N-(2,5-di(piperidin-1-yl)phenyl)furan-2-carboxamide, CSF-1 Receptor Inhibitor IV

344039
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Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
959626-45-0C₂₂H₂₆N₄O₂

Products

Número de referenciaEmbalaje Cant./Env.
344039-5MG Frasco de vidrio 5 mg
Description
OverviewA cell-permeable furan carboxamide compound that acts as a potent, reversible, and ATP-competitive cFMS/CSF-1R inhibitor that blocks cFMS autophosphorylation both in CSF-1/M-CSF-stimulated HEK-293 cells (IC50 = 76 nM) and in cell-free in vitro kinase assays (IC50 = 17 nM).
Catalogue Number344039
Brand Family Calbiochem®
Synonyms5-Cyano-N-(2,5-di(piperidin-1-yl)phenyl)furan-2-carboxamide, CSF-1 Receptor Inhibitor IV
References
ReferencesPatch, R.J., et al. 2007. Bioorg. Med. Chem. Lett. 17, 6070.
Product Information
CAS number959626-45-0
FormYellow solid
Hill FormulaC₂₂H₂₆N₄O₂
Chemical formulaC₂₂H₂₆N₄O₂
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥95% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
344039-5MG 04055977194517

Documentation

cFMS Receptor Inhibitor IV - CAS 959626-45-0 - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

cFMS Receptor Inhibitor IV - CAS 959626-45-0 - Calbiochem Certificados de análisis

CargoNúmero de lote
344039

Referencias bibliográficas

Visión general referencias
Patch, R.J., et al. 2007. Bioorg. Med. Chem. Lett. 17, 6070.
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision08-April-2011 RFH
Synonyms5-Cyano-N-(2,5-di(piperidin-1-yl)phenyl)furan-2-carboxamide, CSF-1 Receptor Inhibitor IV
DescriptionA cell-permeable furan carboxamide compound that acts as a potent, reversible, and ATP-competitive cFMS/CSF-1R inhibitor that blocks cFMS autophosphorylation both in CSF-1/M-CSF-stimulated HEK-293 cells (IC50 = 76 nM) and in cell-free in vitro kinase assays (IC50 = 17 nM).
FormYellow solid
Intert gas (Yes/No) Packaged under inert gas
CAS number959626-45-0
Chemical formulaC₂₂H₂₆N₄O₂
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (5 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesPatch, R.J., et al. 2007. Bioorg. Med. Chem. Lett. 17, 6070.