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203694 bpV(bipy) - Calbiochem

A potent inhibitor of phosphotyrosine phosphatase (Ki = 100 nM for insulin receptor dephosphorylation).

bpV(bipy) - Calbiochem: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: Potassium Bisperoxo(bipyridine)oxovanadate (V), PTEN Inhibitor II, PTP Inhibitors XIV

Primary Target: phosphotyrosine phosphatase
203694
Purchase on Sigma-Aldrich

Descripción

Replacement Information

Tabla espec. clave

Empirical Formula
K[VO(O₂)₂C₁₀H₈N₂] · 3H₂O

Products

Número de referenciaEmbalaje Cant./Env.
203694-5MG Ampolla de plást. 5 mg
Description
OverviewA potent inhibitor of phosphotyrosine phosphatase (Ki = 100 nM for insulin receptor dephosphorylation). An activator of insulin receptor kinase (IRK). Also reported to be a potent inhibitor of PTEN (IC50 = 18 nM).
Catalogue Number203694
Brand Family Calbiochem®
SynonymsPotassium Bisperoxo(bipyridine)oxovanadate (V), PTEN Inhibitor II, PTP Inhibitors XIV
References
ReferencesSchmid, A.C., et al. 2004. FEBS Lett. 566, 35.
Posner, B.I., et al. 1994. J. Biol. Chem. 269, 4596.
Product Information
ATP CompetitiveN
FormYellow to orange solid
Hill FormulaK[VO(O₂)₂C₁₀H₈N₂] · 3H₂O
Chemical formulaK[VO(O₂)₂C₁₀H₈N₂] · 3H₂O
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetphosphotyrosine phosphatase
Primary Target IC<sub>50</sub>18 nM against PTEN
Primary Target K<sub>i</sub>100 nM for phosphotyrosine phosphatase
Purity≥95% by ⁵¹V-NMR
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 20/21/22

Harmful by inhalation, in contact with skin and if swallowed.
S PhraseS: 36

Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsUnstable in solution; reconstitute just prior to use.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
203694-5MG 04055977204414

Documentation

bpV(bipy) - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

bpV(bipy) - Calbiochem Certificados de análisis

CargoNúmero de lote
203694

Referencias bibliográficas

Visión general referencias
Schmid, A.C., et al. 2004. FEBS Lett. 566, 35.
Posner, B.I., et al. 1994. J. Biol. Chem. 269, 4596.

Folleto

Cargo
Protein Phosphatases Technical Bulletin
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision20-May-2008 RFH
SynonymsPotassium Bisperoxo(bipyridine)oxovanadate (V), PTEN Inhibitor II, PTP Inhibitors XIV
DescriptionA potent inhibitor of phosphotyrosine phosphatase activity (Ki = 100 nM for insulin receptor dephosphorylation). An activator of insulin receptor kinase (IRK). Also reported to be a potent inhibitor of PTEN (IC50 = 18 nM).
FormYellow to orange solid
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaK[VO(O₂)₂C₁₀H₈N₂] · 3H₂O
Structure formulaStructure formula
Purity≥95% by ⁵¹V-NMR
SolubilityH₂O (5 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsUnstable in solution; reconstitute just prior to use.
Toxicity Harmful
ReferencesSchmid, A.C., et al. 2004. FEBS Lett. 566, 35.
Posner, B.I., et al. 1994. J. Biol. Chem. 269, 4596.