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605225 Thrombospondin, Human Platelets

605225
Purchase on Sigma-Aldrich

Descripción

Products

Número de referenciaEmbalaje Cant./Env.
605225-25UG Ampolla de plást. 25 μg
Description
OverviewNative thrombospondin purified from human platelets. Adhesive glycoprotein released in response to platelet activation by α-thrombin. An angiogenesis inhibitor that blocks the FGF-induced neovascularization of the rat cornea. An inducer of platelet aggregation. Synthesized by a number of different cells and secreted into the extracellular matrix. Involved in the regulation of cellular proliferation.
Catalogue Number605225
Brand Family Calbiochem®
References
ReferencesArmstrong, L.C., et al. 2002. Mol. Biol. Cell 13, 1893.
Michaund, M. and Poyet, O. 1994. Anticancer Res. 14, 1127.
Castle, V.P., et al. 1993. J. Biol. Chem. 268, 2899.
Koch, A.E., et al. 1993. Pathobiology 61, 1.
Tolsma, S.S., et al. 1993. J. Cell Biol. 122, 497.
Tuszynski, G.P., et al. 1993. J. Cell Biol. 120, 513.
Schon, P., et al. 1992. Eur. J. Cell Biol. 59, 329.
Good, D.J., et al. 1990. Proc. Natl. Acad. Sci. USA 87, 6624.
Product Information
FormLyophlized
FormulationLyophilized from 600 mM NaCl, 20 mM Tris, 1 mM CaCl₂, 20% sucrose, pH 7.8.
Quality LevelMQ100
Biological Information
Purity≥95% by SDS-PAGE
SourcePrepared from platelets that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for 1 week at 4°C or for at least 1 month at -70°C. Product is extremely adherent to surfaces; keep frozen (-70°C) before use and use siliconized surfaces to insure product recovery.
Global Trade Item Number
Número de referencia GTIN
605225-25UG 04055977188486