616520 Sigma-AldrichTRPV4 Antagonist I, RN-1734 - CAS 946387-07-1 - Calbiochem
The TRPV4 Antagonist I, RN-1734, also referenced under CAS 946387-07-1, controls the biological activity of TRPV4. This small molecule/inhibitor is primarily used for Biochemicals applications.
More>> The TRPV4 Antagonist I, RN-1734, also referenced under CAS 946387-07-1, controls the biological activity of TRPV4. This small molecule/inhibitor is primarily used for Biochemicals applications. Less<<Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Sinónimos: 2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide, Transient Receptor Potential Vanilloid-4 Antagonist I, RN1734
Productos recomendados
Descripción
| Replacement Information |
|---|
Tabla espec. clave
| CAS # | Empirical Formula |
|---|---|
| 946387-07-1 | C₁₄H₂₂Cl₂N2O₂S |
Products
| Número de referencia | Embalaje | Cant./Env. | |
|---|---|---|---|
| 616520-10MG | Frasco de vidrio | 10 mg |
| Description | |
|---|---|
| Overview | A cell-permeable benzenesulfonamide compound that selectively antagonizes TRPV4 agonist 4α-PDD- (Cat. No. 524394) stimulated Ca2+ influx (IC50 = 2.3, 3.2 and 5.9 µM, respectively, in HEK293 expressing human, rat, or mouse TRPV4) without affecting the activity of three other human TRP (transient receptor potential) channels, including capsaicin- (Cat. No. 211275) activated TRPV1, camphor-activated TRPV3, and methanol-activated TRPM8 (IC50 >30 µM). |
| Catalogue Number | 616520 |
| Brand Family | Calbiochem® |
| Synonyms | 2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide, Transient Receptor Potential Vanilloid-4 Antagonist I, RN1734 |
| References | |
|---|---|
| References | Vincent, F., et al. 2009. Biochem. Biophys. Res. Commun. 389, 490. |
| Product Information | |
|---|---|
| CAS number | 946387-07-1 |
| Form | Yellow solid |
| Hill Formula | C₁₄H₂₂Cl₂N2O₂S |
| Chemical formula | C₁₄H₂₂Cl₂N2O₂S |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
|---|
| Biological Information | |
|---|---|
| Purity | ≥95% by HPLC |
| Physicochemical Information |
|---|
| Dimensions |
|---|
| Materials Information |
|---|
| Toxicological Information |
|---|
| Safety Information according to GHS |
|---|
| Safety Information |
|---|
| Product Usage Statements |
|---|
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
|---|
| Supplemental Information |
|---|
| Specifications |
|---|
| Global Trade Item Number | |
|---|---|
| Número de referencia | GTIN |
| 616520-10MG | 04055977185249 |
Documentation
TRPV4 Antagonist I, RN-1734 - CAS 946387-07-1 - Calbiochem Ficha datos de seguridad (MSDS)
| Título |
|---|
TRPV4 Antagonist I, RN-1734 - CAS 946387-07-1 - Calbiochem Certificados de análisis
| Cargo | Número de lote |
|---|---|
| 616520 |
Referencias bibliográficas
| Visión general referencias |
|---|
| Vincent, F., et al. 2009. Biochem. Biophys. Res. Commun. 389, 490. |
| Ficha técnica | ||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
|