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505877 (S)-(-)-Raclopride - CAS 84225-95-6 - Calbiochem

505877
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Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
84225-95-6C₁₅H₂₀Cl₂N₂O₃

Products

Número de referenciaEmbalaje Cant./Env.
5058770001 Frasco de vidrio 10 mg
Description
OverviewD2-like dopamine receptor antagonist targeting D2R (pKi =8.0), D3R (pKi = 7.9), and 5-HT1A R (pKi=5.2). Used to explore D2 like receptor mediated effects in neuropathic pain, and in antagonism studies of DA receptors during heroin usage and cocaine. D2 Receptor selectivity in various preps shows IC50 values around 32 nM.
Catalogue Number505877
Brand Family Calbiochem®
SynonymsDopamine Receptor D2 Antagonist, (S)-Raclopride, Raclopride
References
ReferencesDang, Y. H. et al. 2010. Neurosci. 169, 1872.
Platt, D. M. et al. 2010. J. Pharmacol. Exp. Ther. 332, 985.
Product Information
CAS number84225-95-6
FormOff-white solid
Hill FormulaC₁₅H₂₀Cl₂N₂O₃
Chemical formulaC₁₅H₂₀Cl₂N₂O₃
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetD₂
Purity≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
5058770001 04055977263138

Documentation

(S)-(-)-Raclopride - CAS 84225-95-6 - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

(S)-(-)-Raclopride - CAS 84225-95-6 - Calbiochem Certificados de análisis

CargoNúmero de lote
505877

Referencias bibliográficas

Visión general referencias
Dang, Y. H. et al. 2010. Neurosci. 169, 1872.
Platt, D. M. et al. 2010. J. Pharmacol. Exp. Ther. 332, 985.
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision12-September-2013 JSW
SynonymsDopamine Receptor D2 Antagonist, (S)-Raclopride, Raclopride
DescriptionD2-like dopamine receptor antagonist targeting D2R (pKi =8.0), D3R (pKi = 7.9), and 5-HT1A R (pKi=5.2). Used to explore D2 like receptor mediated effects in neuropathic pain, and in antagonism studies of DA receptors during heroin usage and cocaine. D2 Receptor selectivity in various preps shows IC50 values around 32 nM.
FormOff-white solid
CAS number84225-95-6
Chemical formulaC₁₅H₂₀Cl₂N₂O₃
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityDMSO (100 mM) or Ethanol (25 mM)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesDang, Y. H. et al. 2010. Neurosci. 169, 1872.
Platt, D. M. et al. 2010. J. Pharmacol. Exp. Ther. 332, 985.