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14-698M PhKγ2 Protein, active, 250 µg

Active, GST-tagged, recombinant, PhKγ2, amino acids 1-301 containing the mutation F290L, for use in Kinase Assays.

14-698M
250 µg  Also available in 10 μg size (cat#14-698) and in bulk (cat#14-698-K).
Purchase on Sigma-Aldrich

Descripción

Replacement Information
Description
Catalogue Number14-698M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionPhKγ2 Protein, active, 250 µg
OverviewGST-tagged, recombinant, PhKγ2, amino acids 1-301 containing the mutation F290L
References
Product Information
Quality LevelMQ300
Applications
ApplicationActive, GST-tagged, recombinant, PhKγ2, amino acids 1-301 containing the mutation F290L, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Sourceexpressed in E. coli
Entrez Gene Number
Gene Symbol
  • PHKG2
  • PSK-C3
  • PHK-gamma-T
Protein TargetPhKg2
Purification MethodGlutathione-agarose
Target Sub-Familymisc
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P15735 # Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. This isozyme may regulate glycogeneolysis in the testis.
SIZE: 406 amino acids; 46442 Da
SUBUNIT: Polymer of 16 chains, four each of alpha, beta, gamma, and delta. Alpha and beta are regulatory chains, gamma is the catalytic chain, and delta is calmodulin.
DISEASE: SwissProt: P15735 # Defects in PHKG2 are a cause of glycogen storage disease type 9C (GSD9C) [MIM:172471]; also known as autosomal liver glycogenosis. GSD9C is a metabolic disorder manifesting in infancy with hepatomegaly, growth retardation, and elevated plasma aminotransferases and lipids.
SIMILARITY: SwissProt: P15735 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.
Molecular Weight61.37kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation of ZIPtide (Catalog # 12-545)
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C from date of shipment
Packaging Information
Material Size250 µg
Material PackageAlso available in 10 μg size (cat#14-698) and in bulk (cat#14-698-K).
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
14-698M 04053252925375

Documentation