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516566 PPARγ Antagonist III, G3335 - CAS 36099-95-3 - Calbiochem

The PPARγ Antagonist III, G3335, also referenced under CAS 36099-95-3, controls the biological activity of PPARγ.

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: H-Trp-Glu-OH

Primary Target: PPARγ
516566
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Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
36099-95-3C₁₆H₁₉N₃O₅

Products

Número de referenciaEmbalaje Cant./Env.
516566-50MG Ampolla de plást. 50 mg
Description
OverviewA cell-permeable dipeptide that acts as a selective and reversible PPARγ antagonist (KD = ~ 8 µM). Shown to inhibit the agonist activity of Rosiglitazone (100 nM) in a dose-dependent manner (IC50 = 31.9 µM) in transfected COS-7 cells.
Catalogue Number516566
Brand Family Calbiochem®
SynonymsH-Trp-Glu-OH
References
ReferencesYe, F., et al. 2006. Chembiochem 7, 74.
Product Information
CAS number36099-95-3
ATP CompetitiveN
FormWhite solid
Hill FormulaC₁₆H₁₉N₃O₅
Chemical formulaC₁₆H₁₉N₃O₅
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetPPARγ
Primary Target IC<sub>50</sub>kd = ~ 8 µM as PPARγ antagonist
Purity≥98% by TLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
516566-50MG 04055977198195

Documentation

PPARγ Antagonist III, G3335 - CAS 36099-95-3 - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

PPARγ Antagonist III, G3335 - CAS 36099-95-3 - Calbiochem Certificados de análisis

CargoNúmero de lote
516566

Referencias bibliográficas

Visión general referencias
Ye, F., et al. 2006. Chembiochem 7, 74.
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision26-August-2024 JSW
SynonymsH-Trp-Glu-OH
DescriptionA cell-permeable dipeptide that acts as a selective and reversible PPARγ antagonist (KD ~8 µM). Shown to inhibit the agonist activity of Rosiglitazone (100 nM) in a dose-dependent manner (IC50 = 31.9 µM) in transfected COS-7 cells.
FormWhite solid
Intert gas (Yes/No) Packaged under inert gas
CAS number36099-95-3
Chemical formulaC₁₆H₁₉N₃O₅
Structure formulaStructure formula
Purity≥98% by TLC
SolubilityH₂O (30 mg/ml). Addition of a small amount of acid or base may be required for complete solubilization.
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesYe, F., et al. 2006. Chembiochem 7, 74.