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520219 PPACK II, Trifluoroacetate Salt - CAS 74392-49-7 - Calbiochem

PPACK II, Trifluoroacetate Salt, CAS 74392-49-7, is a potent, specific, and irreversible inhibitor of plasma and glandular kallikreins.

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Primary Target: Plasma and glandular kallikreins
520219
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Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
74392-49-7C₂₅H₃₃ClN₆O₃ . 2CF₃COOH

Products

Número de referenciaEmbalaje Cant./Env.
520219-10MG Ampolla de plást. 10 mg
Description
OverviewPotent and specific irreversible inhibitor of plasma and glandular kallikreins. Also available as a 10 mM solution in H2O (Cat. No. 508573).
Catalogue Number520219
Brand Family Calbiochem®
References
ReferencesByrne, R.E., and Scanu, A.M. 1989. J. Lipid Res. 30, 109.
Scicli, G., et al. 1989. Adv. Exp. Med. Biol. 247B, 217.
Gibson, T.R., et al. 1987. Endocrinology 120, 764.
Kettner, G., and Shaw, E. 1981. Methods Enzymol. 80, 826.
Product Information
CAS number74392-49-7
ATP CompetitiveN
FormOff-white solid
Hill FormulaC₂₅H₃₃ClN₆O₃ . 2CF₃COOH
Chemical formulaC₂₅H₃₃ClN₆O₃ . 2CF₃COOH
ReversibleN
Quality LevelMQ100
Applications
ApplicationPPACK II, Trifluoroacetate Salt, CAS 74392-49-7, is a potent, specific, and irreversible inhibitor of plasma and glandular kallikreins.
Biological Information
Primary TargetPlasma and glandular kallikreins
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Peptide SequenceH-D-Phe-Phe-Arg-chloromethylketone, 2TFA
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
520219-10MG 04055977271928

Documentation

PPACK II, Trifluoroacetate Salt - CAS 74392-49-7 - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

PPACK II, Trifluoroacetate Salt - CAS 74392-49-7 - Calbiochem Certificados de análisis

CargoNúmero de lote
520219

Referencias bibliográficas

Visión general referencias
Byrne, R.E., and Scanu, A.M. 1989. J. Lipid Res. 30, 109.
Scicli, G., et al. 1989. Adv. Exp. Med. Biol. 247B, 217.
Gibson, T.R., et al. 1987. Endocrinology 120, 764.
Kettner, G., and Shaw, E. 1981. Methods Enzymol. 80, 826.
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision11-October-2013 JSW
DescriptionPotent and specific irreversible inhibitor of plasma and glandular kallikreins. Inhibits the cleavage of atrial naturiuretic peptide (ANP 1-126) by kallikreins. Also inhibits adrenal kininogenase, a kallikrein-like enzyme.
FormOff-white solid
CAS number74392-49-7
Chemical formulaC₂₅H₃₃ClN₆O₃ . 2CF₃COOH
Peptide SequenceH-D-Phe-Phe-Arg-chloromethylketone, 2TFA
Purity≥95% by HPLC
SolubilityH₂O (100 mg/ml)
Storage Protect from moisture
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Toxicity Standard Handling
ReferencesByrne, R.E., and Scanu, A.M. 1989. J. Lipid Res. 30, 109.
Scicli, G., et al. 1989. Adv. Exp. Med. Biol. 247B, 217.
Gibson, T.R., et al. 1987. Endocrinology 120, 764.
Kettner, G., and Shaw, E. 1981. Methods Enzymol. 80, 826.