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14-778M PP5, active

PP5, active: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
14-778M
250 µg  Also available in 10μg size as catalog # 14-778 and in 250 μg as catalog # 14-778M.
Purchase on Sigma-Aldrich

Descripción

Replacement Information
Description
Catalogue Number14-778M
Trade Name
  • Upstate
DescriptionPP5, active
OverviewThis protein is a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family.
Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine
residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of
this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants.
References
Product Information
PresentationProtein in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Quality LevelMQ100
Applications
Key Applications
  • Phosphatase Assay
Biological Information
SourceN-terminal GST-tagged, recombinant, full length, human PP5, expressed in E. coli cells.
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Gene Symbol
  • PP5
  • PPP5C
  • PPP5
  • PPT
Purification MethodPurified using glutathione agarose.
UniProt Number
Molecular Weight83.8 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by the release of phosphate from the substrate 6,8-difluoro-4-methylumbelliferyl phosphate (DiFMUP)
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C
Packaging Information
Material Size250 µg
Material PackageAlso available in 10μg size as catalog # 14-778 and in 250 μg as catalog # 14-778M.
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
14-778M 04053252738982

Productos y aplicaciones relacionados

Alternative Packsize

Número de referencia Descripción
14-778 PP5, active

Familias de productos

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Categorías

Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Phosphatases
Life Science Research > Proteins and Enzymes > Purified Phosphatases