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539522 PKCε Translocation Inhibitor Peptide - Calbiochem

The PKCε Translocation Inhibitor Peptide, Negative Control controls the biological activity of PKCε. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: Protein Kinase Cε Translocation Inhibitor I, EAVSLKPT, PKCε Translocation Inhibitor I, PKCε-RACK2 Interaction Inhibitor I

Primary Target: PKCε Translocation
539522
Purchase on Sigma-Aldrich

Descripción

Replacement Information

Tabla espec. clave

Empirical Formula
C₃₇H₆₅N₉O₁₃

Products

Número de referenciaEmbalaje Cant./Env.
539522-5MG Ampolla de plást. 5 mg
Description
OverviewAn octapeptide that selectively inhibits the translocation of protein kinase Cε to subcellular sites in a reversible manner. Inhibition of PKCε translocation is known to specifically block phorbol ester- or norepinephrine-mediated regulation of contraction in cardiomyocytes.
Catalogue Number539522
Brand Family Calbiochem®
SynonymsProtein Kinase Cε Translocation Inhibitor I, EAVSLKPT, PKCε Translocation Inhibitor I, PKCε-RACK2 Interaction Inhibitor I
References
ReferencesYedovitzky, M., et al. 1997. J. Biol. Chem. 272, 1417.
Johnson, J.A., et al. 1996. J. Biol. Chem. 271, 24962.
Product Information
ATP CompetitiveN
DeclarationSold under license of U.S. Patent 5,783,405.
FormWhite lyophilized solid
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₃₇H₆₅N₉O₁₃
Chemical formulaC₃₇H₆₅N₉O₁₃
Hygroscopic Hygroscopic
ReversibleY
Quality LevelMQ100
Applications
Biological Information
Primary TargetPKCε Translocation
Purity≥97% by HPLC
Physicochemical Information
Cell permeableN
Peptide SequenceH-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
539522-5MG 04055977194630

Documentation

PKCε Translocation Inhibitor Peptide - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

PKCε Translocation Inhibitor Peptide - Calbiochem Certificados de análisis

CargoNúmero de lote
539522

Referencias bibliográficas

Visión general referencias
Yedovitzky, M., et al. 1997. J. Biol. Chem. 272, 1417.
Johnson, J.A., et al. 1996. J. Biol. Chem. 271, 24962.

Citas

Título
  • Lawrence, K.M., et al. 2005. FASEB Journal 19, 831-833.
  • Dai, Y., et al. 2004. Journal of Neuroscience 24, 4293.
    		•
    Ficha técnica

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision05-September-2008 RFH
    SynonymsProtein Kinase Cε Translocation Inhibitor I, EAVSLKPT, PKCε Translocation Inhibitor I, PKCε-RACK2 Interaction Inhibitor I
    DescriptionAn octapeptide that selectively inhibits the translocation of PKCε to subcellular sites. Inhibition of PKCε translocation is known to specifically block phorbol ester or norepinephrine-mediated regulation of contraction in cardiomyocytes.
    FormWhite lyophilized solid
    FormulationSupplied as a trifluoroacetate salt.
    Chemical formulaC₃₇H₆₅N₉O₁₃
    Peptide SequenceH-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH
    Purity≥97% by HPLC
    SolubilityH₂O (3 mg/ml)
    Storage +2°C to +8°C
    Hygroscopic
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 6 months at -20°C.
    Toxicity Standard Handling
    ReferencesYedovitzky, M., et al. 1997. J. Biol. Chem. 272, 1417.
    Johnson, J.A., et al. 1996. J. Biol. Chem. 271, 24962.
    Citation
  • Lawrence, K.M., et al. 2005. FASEB Journal 19, 831-833.
  • Dai, Y., et al. 2004. Journal of Neuroscience 24, 4293.
    		•