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33-055 PIP4-Kinase HTRF Assay

The PIP4 Kinase HTRF Assay kit provides a method for assaying PI(5)P-4 kinases in a homogenous 1920 well format. Suitable for screening of potential inhibitors of these enzymes.

PIP4-Kinase HTRF Assay: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
33-055
1920 wells  Kit capacity: 1920 wells
Purchase on Sigma-Aldrich

Descripción

Replacement Information
Description
Catalogue Number33-055
Brand Family Upstate
Trade Name
  • HTRF
  • Upstate
DescriptionPIP4-Kinase HTRF Assay
References
Product Information
Components
  • Reaction Buffer (4X)
  • DM A Detection Reagent
  • DM C Detection Reagent
  • DM E Detection Reagent
  • Phosphatidylinositol 5-phosphate (1mM)
  • Phosphatidylserine (1mM)
  • Stop Reagent D
Detection methodHTRF
Quality LevelMQ100
Applications
ApplicationThe PIP4 Kinase HTRF Assay kit provides a method for assaying PI(5)P-4 kinases in a homogenous 1920 well format. Suitable for screening of potential inhibitors of these enzymes.
Key Applications
  • Kinase Assay
Biological Information
Species Reactivity
  • Human
  • Mouse
Analytes Available
  • PIP4 Kinase
Entrez Gene Number
Entrez Gene SummaryPhosphatidylinositol 5-phosphate 4-kinase type-2 alpha
catalyzes the phosphorylation of phosphatidylinositol 5-phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin-stimulated glucose uptake by lowering the levels of PtdIns5P. May be involved in thrombopoiesis, and the terminal maturation of megakaryocytes and regulation of their size.
Gene Symbol
  • PIP4K2α
Target Sub-FamilyPI3K/PI4K
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions12 months at -70°C
Packaging Information
Material Size1920 wells
Material PackageKit capacity: 1920 wells
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
33-055 04053252374524

Documentation

PIP4-Kinase HTRF Assay Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

PIP4-Kinase HTRF Assay Certificados de análisis

CargoNúmero de lote
PIP4-Kinase HTRF Assay (1920 wells) - 2029659 2029659
PIP4-Kinase HTRF Assay (1920 wells) - 2029669 2029669
PIP4-Kinase HTRF Assay (1920 wells) - 2051188 2051188
PIP4-Kinase HTRF Assay (1920 wells) - 2060764 2060764
PIP4-Kinase HTRF Assay (1920 wells) - 2066705 2066705
PIP4-Kinase HTRF Assay (1920 wells) - 2070423 2070423
PIP4-Kinase HTRF Assay (1920 wells) - 2070425 2070425
PIP4-Kinase HTRF Assay (1920 wells) - 2196515 2196515
PIP4-Kinase HTRF Assay (1920 wells) - 2382912 2382912
PIP4-Kinase HTRF Assay (1920 wells) - 2422043 2422043
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Productos y aplicaciones relacionados

Alternative Packsize

Número de referencia Descripción
33-054 PIP4-Kinase HTRF Assay

Familias de productos

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HTRF™

Categorías

Life Science Research > Protein Detection and Quantification > Activity Assays > Kinase Assays
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Enzyme Assay Kits and Reagents