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528822 PARP Inhibitor XII - CAS 489457-67-2 - Calbiochem

The PARP Inhibitor XII, also referenced under CAS 489457-67-2, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: 3-(4-Chlorophenyl)quinoxaline-5-carboxamide

528822
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Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
489457-67-2C₁₅H₁₀ClN₃O

Products

Número de referenciaEmbalaje Cant./Env.
528822-5MG Frasco de vidrio 5 mg
Description
OverviewA potent quinoxaline-based PARP inhibitor with a ~5-fold selectivity towards PARP-2 over PARP-1 (IC50 = 7 and 33 nM, respectively). Reported to be brain-permeant and exhibit good pharmacokinetics.
Catalogue Number528822
Brand Family Calbiochem®
Synonyms3-(4-Chlorophenyl)quinoxaline-5-carboxamide
References
ReferencesIshida, J., et al. 2006. Bioorg. Med. Chem. 14, 1378.
Iwashita, A., et al. 2005. FEBS Lett. 579, 1389.
Product Information
CAS number489457-67-2
FormLight brown solid
Hill FormulaC₁₅H₁₀ClN₃O
Chemical formulaC₁₅H₁₀ClN₃O
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥95% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
528822-5MG 04055977196634

Documentation

PARP Inhibitor XII - CAS 489457-67-2 - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

PARP Inhibitor XII - CAS 489457-67-2 - Calbiochem Certificados de análisis

CargoNúmero de lote
528822

Referencias bibliográficas

Visión general referencias
Ishida, J., et al. 2006. Bioorg. Med. Chem. 14, 1378.
Iwashita, A., et al. 2005. FEBS Lett. 579, 1389.
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision18-April-2011 RFH
Synonyms3-(4-Chlorophenyl)quinoxaline-5-carboxamide
DescriptionA potent quinoxaline-based PARP inhibitor with a ~5-fold selectivity towards PARP-2 over PARP-1 (IC50 = 7 and 33 nM, respectively). Reported to be brain-permeant and exhibit good pharmacokinetics.
FormLight brown solid
Intert gas (Yes/No) Packaged under inert gas
CAS number489457-67-2
Chemical formulaC₁₅H₁₀ClN₃O
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (10 mg/ml)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Irritant
ReferencesIshida, J., et al. 2006. Bioorg. Med. Chem. 14, 1378.
Iwashita, A., et al. 2005. FEBS Lett. 579, 1389.