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300270 PARP Inhibitor III, DPQ - CAS 129075-73-6 - Calbiochem

The PARP Inhibitor III, DPQ, also referenced under CAS 129075-73-6, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: 3,4-Dihydro-5[4-(1-piperindinyl)butoxy]-1(2H)-isoquinoline

Primary Target: PARP
300270
Purchase on Sigma-Aldrich

Descripción

Replacement Information

Tabla espec. clave

CAS #Empirical Formula
129075-73-6C₁₈H₂₆N₂O₂

Products

Número de referenciaEmbalaje Cant./Env.
300270-1MG Ampolla de plást. 1 mg
Description
OverviewA potent and selective inhibitor of poly(ADP-ribose) polymerase (PARP; IC50 = 40 nM). Significantly reduces infarcet volume in rat focual cerebrale ischemia model.
Catalogue Number300270
Brand Family Calbiochem®
Synonyms3,4-Dihydro-5[4-(1-piperindinyl)butoxy]-1(2H)-isoquinoline
References
ReferencesEliasson, M.J., et al. 1997. Nat. Med. 3, 1089.
Takahashi, K., et al. 1997. J. Cereb. Blood Flow Metabl. 17, 1137.
Suto, M.J., et al. 1991. Anticancer Drug Des. 6, 107.
Product Information
CAS number129075-73-6
ATP CompetitiveN
FormOff-white solid
Hill FormulaC₁₈H₂₆N₂O₂
Chemical formulaC₁₈H₂₆N₂O₂
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetPARP
Primary Target IC<sub>50</sub>40 nM
Purity≥90% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 20/21/22

Harmful by inhalation, in contact with skin and if swallowed.
S PhraseS: 36

Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Número de referencia GTIN
300270-1MG 04055977198010

Documentation

PARP Inhibitor III, DPQ - CAS 129075-73-6 - Calbiochem Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

PARP Inhibitor III, DPQ - CAS 129075-73-6 - Calbiochem Certificados de análisis

CargoNúmero de lote
300270

Referencias bibliográficas

Visión general referencias
Eliasson, M.J., et al. 1997. Nat. Med. 3, 1089.
Takahashi, K., et al. 1997. J. Cereb. Blood Flow Metabl. 17, 1137.
Suto, M.J., et al. 1991. Anticancer Drug Des. 6, 107.
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision17-June-2008 RFH
Synonyms3,4-Dihydro-5[4-(1-piperindinyl)butoxy]-1(2H)-isoquinoline
DescriptionA very potent and selective poly(ADP-ribose)polymerase (PARP) inhibitor (IC50 = 40 nM). Significantly reduces infarcet volume in rat focual cerebrale ischemia model.
FormOff-white solid
CAS number129075-73-6
Chemical formulaC₁₈H₂₆N₂O₂
Structure formulaStructure formula
Purity≥90% by HPLC
SolubilityDMSO (5 mg/ml)
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 1 month at -20°C.
Toxicity Harmful
ReferencesEliasson, M.J., et al. 1997. Nat. Med. 3, 1089.
Takahashi, K., et al. 1997. J. Cereb. Blood Flow Metabl. 17, 1137.
Suto, M.J., et al. 1991. Anticancer Drug Des. 6, 107.